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GenomicsGlobal epigenomic analysis of primary human pancreatic islets provides insights into type 2 diabetes susceptibility loci
Identifying cis-regulatory elements is important to understand how human pancreatic islets modulate gene expression in physiologic or pathophysiologic (e.g., diabetic) conditions. We conducted genome-wide analysis of DNase I hypersensitive sites, histone H3 lysine methylation marks (K4me1, K4me3, K7...
ORGANISM(S): Homo sapiens 
2010-11-02 | E-GEOD-23784 | biostudies-arrayexpress
UnknownPreclinical validation of a microarray method for full molecular karyotyping of blastomeres in a 24-h protocol.
Not available
S-EPMC2839907 | biostudies-literature
UnknownSynthesis without meta-analysis (SWiM) in systematic reviews: reporting guideline.
Not available
S-EPMC7190266 | biostudies-literature
UnknownPhosphonoacetate Modifications Enhance the Stability and Editing Yields of Guide RNAs for Cas9 Editors.
Not available
S-EPMC10734248 | biostudies-literature
UnknownEvolution and host-specific adaptation of <i>Pseudomonas aeruginosa</i>.
Not available
S-EPMC7618370 | biostudies-literature
UnknownSpatial and temporal transmission dynamics of respiratory syncytial virus in New Zealand before and after the COVID-19 pandemic.
Not available
S-EPMC11555088 | biostudies-literature
UnknownFatal perinatal mitochondrial cardiac failure caused by recurrent de novo duplications in the ATAD3 locus.
Not available
S-EPMC7875323 | biostudies-literature
UnknownRetrospective delirium ascertainment from case notes: a retrospective cohort study.
Not available
S-EPMC8166612 | biostudies-literature
GenomicsGoT2D: Genetics of Type 2 Diabetes, a study of the the genetic architecture of type 2 diabetes using low pass whole genome sequencing and high density SNP genotyping in 2,657 individuals.
The Genetics of Type 2 Diabetes Consortium (GoT2D) is a collaboration between the University of Michigan, the Broad Institute and the Wellcome Trust Centre for Human Genetics. The overall aim is to extend upon recent efforts, such as genome-wide association studies (GWAS) and large scale meta-analys...
EGAS00001001459 | EGA
Genomicsena-DATASET-GoT2D/T2D-GENES-09-07-2016-02:03:47:226-1135 - samples
The GoT2D study includes ~2800 samples, half T2D cases and half T2D controls, of Northern European ancestry sequenced over 3 three technologies: deep whole exome sequencing, low-pass (4x) whole genome sequencing, and OMNI 2.5M genotyping. Samples were ascertained to be phenotypically "extreme" (e.g....
EGAD00001002247 | EGA
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