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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
UnknownMethane in groundwater before, during, and after hydraulic fracturing of the Marcellus Shale.
Not available
S-EPMC6142237 | biostudies-literature
UnknownEffects of a brief multimedia psychoeducational intervention on the attitudes and interest of patients with cancer regarding clinical trial participation: a multicenter randomized controlled trial.
Not available
S-EPMC4577714 | biostudies-literature
MetabolomicsLC-MS groundwater analysis 'Hainich Critical Zone exploratory', dataset extension (MS1)

Understanding biogeochemical conversions of dissolved organic matter (DOM) in aquifers is paramount for the effective management of groundwater supplies. On its passage through the critical zone, DOM is subject to biogeochemical conversions and therefore carries cross-habitat information useful f...

2024-10-17 | MTBLS11375 | MetaboLights
UnknownA Robust e-Epidemiology Tool in Phenotyping Heart Failure with Differentiation for Preserved and Reduced Ejection Fraction: the Electronic Medical Records and Genomics (eMERGE) Network.
Not available
S-EPMC4651838 | biostudies-literature
TranscriptomicsHuman iPSC-Derived Cerebellar Neurons from a Patient with Ataxia-Telangiectasia Reveal Disrupted Gene Regulatory Networks
Control (CRL2429 C11) and A-T (MC3/AT30) iPSC were differentiated according to Erceg et al to generate cerebellar precursors Examination of changes in gene expression after a 34 day differentiation protocol in control and A-T iPSC
ORGANISM(S): Homo sapiens 
2017-10-02 | E-GEOD-75852 | biostudies-arrayexpress
MetabolomicsAntiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing.

METHODS: Using untargeted high-resolution liquid chromatography coupled with...

2022-02-10 | MTBLS718 | MetaboLights
UnknownEarly Life Food Desert Status Is Associated With Alpha and Gamma-Tocopherol Levels and Infant Lung Function.
Not available
S-EPMC12853406 | biostudies-literature
TranscriptomicsMicroglia infection of Listeria monocytogenes is regulated by ActA virulence factor and TNF-α.
Cerebral listeriosis is characterized by neuronal apoptosis and microglial cell activation, but little is known about the bacterial virulence factors involved in this process and how bacterial dissemination is controlled. Here, we show that the cellular target of Listeria monocytogenes (LM) in mur...
ORGANISM(S): Mus musculus 
2011-10-02 | E-GEOD-32505 | biostudies-arrayexpress
UnknownSearch for charged Higgs bosons in e+e- collisions at [Formula: see text].
Not available
S-EPMC4371074 | biostudies-literature
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