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ProteomicsEndocytic Turnover of Endothelial Cell-Membrane Proteins as a Driver of Blood Brain Barrier Specialization and Dysfunction
The blood-brain barrier (BBB), formed primarily by specialized brain endothelial cells (BEC), exerts essential functions for proper brain activity, including nutrient transport, signal transduction, immune cell transmigration and pathogen restriction. While these functions are known to be regulated ...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-05-15 | PXD067112 | Pride
Blood-brain barrier Brain endothelial cells Endocytic turnover rate 
TranscriptomicsRNAseq of small intestinal organoids from mice treated with the cytokines IL-13 and IL-22 for 72 hours in combination with the BMP signaling inhibitor DMH1
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. The changes in cellular composition is driven by immune cell derived cytokines. Here we use signatur...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-9185 | biostudies-arrayexpress
TranscriptomicsRNAseq of camta3/dsc1/dsc2 after elf18 or mock treatment, against wt control, at 10, 30 and 90 minutes
The general stress response is a major transcriptional reprogramming in elicitor response. CAMTA3 is a key regulator of the general stress response, and is guarded by Dominant Suppressor of CAMTA3 1 and DSC2. Here we assay transcriptional response to elf18, an elicitor, at 10 (primary response), 30 ...
ORGANISM(S): Arabidopsis thaliana 
2022-12-31 | E-MTAB-10210 | biostudies-arrayexpress
TranscriptomicsTonsil Atlas FASTQ files
This repository contains all the FASTQ files for the five data modalities (scRNA-seq, scATAC-seq, Multiome, CITE-seq+scVDJ-seq, and spatial transcriptomics) used in the article \\"An Atlas of Cells in The Human Tonsil,\\" published in Immunity in 2024. Inspired by the TCGA barcodes, we have named ea...
ORGANISM(S): Homo sapiens 
2024-05-02 | E-MTAB-13687 | biostudies-arrayexpress
UnknownMDMA-assisted therapy for moderate to severe PTSD: a randomized, placebo-controlled phase 3 trial.
Not available
S-EPMC10579091 | biostudies-literature
UnknownMDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study.
Not available
S-EPMC8205851 | biostudies-literature
UnknownMetformin and Time to Sustained Recovery in Adults With COVID-19: The ACTIV-6 Randomized Clinical Trial.
Not available
S-EPMC12261116 | biostudies-literature
UnknownTime to Sustained Recovery Among Outpatients With COVID-19 Receiving Montelukast vs Placebo: The ACTIV-6 Randomized Clinical Trial.
Not available
S-EPMC11581631 | biostudies-literature
UnknownHigher-Dose Fluvoxamine and Time to Sustained Recovery in Outpatients With COVID-19: The ACTIV-6 Randomized Clinical Trial.
Not available
S-EPMC10656670 | biostudies-literature
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