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ProteomicsScreening of rheumatoid arthritis patients sera against citrullinated fibrinogen peptides using ImmunoCAP ISAC system
Citrullinated and unmodified peptides (>95% purity, ProImmune AB) were immobilized onto a chemically modified glass slide, sera from RA patients and healthy controls were applied into the reactions sites and fluorescence intensity after incubation with anti-human IgG antibody was acquired in a las...
ORGANISM(S): Homo sapiens 
2015-10-25 | E-MTAB-3606 | biostudies-arrayexpress
MetabolomicsSubcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remains the world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of multidrug therapy. Difficulty visualizing the subcellular localization of antibiotics in infected host cells means t...
2020-12-07 | MTBLS959 | MetaboLights
UnknownExclusion of deep vein thrombosis using the Wells rule in clinically important subgroups: individual patient data meta-analysis.
Not available
S-EPMC3948465 | biostudies-literature
TranscriptomicsGene expression in clonogenic versus non-clonogenic in pooled early passage OCI/AML-4 single cells
Identification of genes that regulate clonogenicity of AML cells is hindered by the difficulty of isolating pure populations of cells with defined proliferative abilities. Using early passages of the OCI/AML-4 cell line we sought to determine genes differentially expressed between clonogenic and no...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-28612 | biostudies-arrayexpress
UnknownHeavy carbon nanodots 2: plasmon amplification in Quanta Plate™ wells and the correlation with the synchronous scattering spectrum.
Not available
S-EPMC6398338 | biostudies-literature
TranscriptomicsPhenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling
Multiple genetic and environmental factors play a role in the development and progression of ParkinsonM-bM-^@M-^Ys disease (PD). The main neuropathological hallmark of PD is the degeneration of dopaminergic (DAergic) neurons in the substantia nigra pars compacta (SN). To study genetic and molecular ...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-43368 | biostudies-arrayexpress
TranscriptomicsHigh-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq using drop-based microfluidics
The importance of single-cell level data is increasingly appreciated, and significant advances in this direction have been made in recent years. Common to these technologies is the need to physically segregate individual cells into containers, such as wells or chambers of a micro-fluidics chip. High...
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-62050 | biostudies-arrayexpress
TranscriptomicsThe effect of prohibitin overexpression in Caco2-BBE intestinal epithelial cells
To determine the effect of prohibitin overexpression on global gene expression in Caco2-BBE intestinal epithelial cells. 4 individual wells of Caco2-BBE cells, passage 41, were transfected with either empty vector (pcDNA4) or prohibitin/pcDNA4 for 72 hours. Total RNA isolated from 4 wells of cells/...
ORGANISM(S): Homo sapiens 
2010-06-19 | E-GEOD-12605 | biostudies-arrayexpress
ProteomicsIdentification of Plasma Biomarkers from Rheumatoid Arthritis Patients Using an Optimized SWATH Proteomics Workflow
Rheumatoid arthritis (RA) is a systemic autoimmune and inflammatory disease. Plasma biomarkers are critical for understanding disease mechanisms, treatment effects, and diagnosis. Mass spectrometry-based proteomics is a powerful tool for unbiased biomarker discovery. However, plasma proteomics is si...
ORGANISM(S): Homo sapiens (Human) 
2023-10-25 | PXD045171 | Pride
Rheumatoid arthritis  mass spectrometry  proteomics  swath  dia  plasma  biomarker  protein isoform 
TranscriptomicsSHAE004: SARS-CoV, SARS-dORF6 and SARS-BatSRBD infection of HAE cultures.
HAE cultures were infected with SARS-CoV, SARS-dORF6 or SARS-BatSRBD and were directly compared to A/CA/04/2009 H1N1 influenza-infected cultures. Cell samples were collected at various hours post-infection for analysis. Time Points = 0, 12, 24, 36, 48, 60, 72, 84 and 96 hrs post-infection for SARS-...
ORGANISM(S): Homo sapiens 
2013-07-31 | E-GEOD-47962 | biostudies-arrayexpress
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