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TranscriptomicsThe RON receptor tyrosine kinase promotes metastasis by triggering epigenetic reprogramming through the thymine glycosylase MBD4 (gene expression array)
Metastasis is the major cause of death in cancer patients, yet the genetic/epigenetic programs that drive metastasis are poorly understood. Here, we report a novel epigenetic reprogramming pathway that is required for breast cancer metastasis. Concerted differential DNA methylation is initiated by a...
ORGANISM(S): Homo sapiens 
2014-01-02 | E-GEOD-52567 | biostudies-arrayexpress
TranscriptomicsThe RON receptor tyrosine kinase promotes metastasis by triggering epigenetic reprogramming through the thymine glycosylase MBD4 (RNA-Seq)
Metastasis is the major cause of death in cancer patients, yet the genetic/epigenetic programs that drive metastasis are poorly understood. Here, we report a novel epigenetic reprogramming pathway that is required for breast cancer metastasis. Concerted differential DNA methylation is initiated by a...
ORGANISM(S): Homo sapiens 
2014-01-02 | E-GEOD-52687 | biostudies-arrayexpress
TranscriptomicsPatient-derived tumor grafts authentically reflect tumor pathology, growth, metastasis, and disease outcomes
This SuperSeries is composed of the following subset Series: GSE32530: Primary tumorgrafts as advanced models for breast cancer that authentically reflect tumor histopathology, growth, metastasis, and patient outcomes (copy number) GSE32531: Patient-derived tumor grafts authentically reflect tumor p...
ORGANISM(S): Homo sapiens 
2011-10-22 | E-GEOD-32532 | biostudies-arrayexpress
ProteomicsA Network Approach to Identify Biomarkers of Differential Chemotherapy Response Using Patient-Derived Xenograft Models of Triple Negative Breast Cancer
The authors develop a novel computational algorithm that identified two signatures of differential response to platinum-based and taxane chemotherapies in breast cancer.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-10-15 | MSV000088233 | MassIVE
TranscriptomicsEndocrine response in invasive lobular carcinoma is characterized by unique estrogen-mediated gene expression and de novo tamoxifen resistance (SUM44)
Invasive lobular carcinoma (ILC) is a histological subtype of breast cancer that is frequently associated with favorable outcomes, as ~90% of ILC express the estrogen receptor (ER). However, recent retrospective analyses suggest that ILC patients receiving adjuvant endocrine therapy may not benefit ...
ORGANISM(S): Homo sapiens 
2014-01-16 | E-GEOD-50694 | biostudies-arrayexpress
TranscriptomicsEndocrine response in invasive lobular carcinoma is characterized by unique estrogen-mediated gene expression and de novo tamoxifen resistance (MM134)
Invasive lobular carcinoma (ILC) is a histological subtype of breast cancer that is frequently associated with favorable outcomes, as ~90% of ILC express the estrogen receptor (ER). However, recent retrospective analyses suggest that ILC patients receiving adjuvant endocrine therapy may not benefit ...
ORGANISM(S): Homo sapiens 
2014-01-16 | E-GEOD-50693 | biostudies-arrayexpress
UnknownThe RON receptor tyrosine kinase promotes metastasis by triggering epigenetic reprogramming through the thymine glycosylase MBD4 (gene expression array)
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-52567 | biostudies-other
UnknownPatient-derived tumor grafts authentically reflect tumor pathology, growth, metastasis, and disease outcomes (expression)
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-32531 | biostudies-other
Genomicsena-DATASET-CRUK-CI-22-07-2020-08:24:26:904-1617 - samples
RNA-SEQ for the Caldas Lab breast cancer PDTX collection. This includes both single and paired end runs
EGAD00001006307 | EGA
Genomicsena-DATASET-CRUK-CI-15-09-2016-11:30:35:546-51 - samples
Breast cancer PDTX sequencing data from Bruna et al, Cell 2016 - Exome Sequencing - Shallow Whole Genome Sequencing - RRBS Methylation Sequencing
EGAD00001002685 | EGA
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