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ProteomicsA Network Approach to Identify Biomarkers of Differential Chemotherapy Response Using Patient-Derived Xenograft Models of Triple Negative Breast Cancer
The authors develop a novel computational algorithm that identified two signatures of differential response to platinum-based and taxane chemotherapies in breast cancer.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-10-15 | MSV000088233 | MassIVE
TranscriptomicsPrimary Mammary Epithelial Cells: Control vs 1023-Treated
Gene expression profiling of primary mammary epithelial cells treated for 72 hours with compound 1023 compared to DMSO. Goal was to determine genes differntially regulated by treatment with the novel compound, 1023. Two-condition experiment, DMSO vs. 1023. Biological replicates: 2 control replicate...
ORGANISM(S): Mus musculus 
2012-12-31 | E-GEOD-39249 | biostudies-arrayexpress
TranscriptomicsA phenotype-based model for rational selection of novel targeted therapies in treating aggressive breast cancer
Treating unselected cancer patients with new drugs dilutes proof of efficacy when only a fraction of patients respond to therapy. We conducted a meta-analysis on eight primary breast cancer microarray datasets representing diverse breast cancer phenotypes. We present a high-throughput protocol which...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-18331 | biostudies-arrayexpress
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