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CD73 (ecto-5'-nucleotidase) is a metabolic immune checkpoint that dephosphorylates AMP to produce adenosine. Adenosine plays a pivotal role in immunosuppressive tumor microenvironment (TME) through adenosine receptors expressed on various immune cells. AB680, a specific CD73 inhibitor, is currently ...
2025-08-04 | MTBLS11084 | MetaboLights
The piling of Fuzhuan brick tea is a traditional fermentation process. These LC-MS data help us know the chemical diversity of piling teas.
ORGANISM(S): Camellia Sinensis Var. Sinensis (ncbitaxon:542762) 
2022-12-09 | MSV000090874 | GNPS
Colorectal cancer (CRC) is one of the most common cancers worldwide with poor survival and limited therapeutic options. There is an urgent need for developing novel therapeutic agents against CRC with good treatment efficiency and low toxicity. Odoroside A (OA) is an active compound isolated from th...
ORGANISM(S): Homo Sapiens 
2019-01-09 | PXD012252 |
Comprehensive single-cell metabolic profiling is critical for revealing phenotypic heterogeneity and elucidating the molecular mechanisms underlying biological processes. However, single-cell metabolomics remains challenging because of the limited metabolite coverage and inability to discriminate is...
2026-08-14 | MTBLS8113 | MetaboLights
Dark teas are prepared by a microbial fermentation process. Flavan-3-ol B-ring fission analogues (FBRFAs) are some of the key bioactive constituents that characterise dark teas. The microbes and biosynthetic precursors involved in the formation of FBRFAs are not known. Using a unique solid-state fer...
ORGANISM(S): Trametes Hirsuta (ncbitaxon:5327) Cladosporium Sp. (ncbitaxon:1707700) Cladosporium Tenuissimum (ncbitaxon:70808) Aspergillus Niger (ncbitaxon:5061) Eurotium Cristatum (ncbitaxon:41421) Candida Metapsilosis (ncbitaxon:273372) Penicillium Steckii (ncbitaxon:303698) Penicillium Oxalicum (ncbitaxon:69781) Aspergillus Sp. (ncbitaxon:5065) Bjerkandera Adusta (ncbitaxon:5331) Aspergillus Ochraceus (ncbitaxon:40380) Penicillium Sp. (ncbitaxon:5081) 
2020-05-02 | MSV000085360 | GNPS
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