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ProteomicsDown-regulated Glutathione Peroxidase-4 by Graphene Quantum Dots Inducing Ferroptosis in Macrophages
to explore the mechanism, we analyzed the differences in the protein profile of macrophages using tandem mass tags (TMT) proteomics.
ORGANISM(S): Mus Musculus 
2020-12-23 | PXD023303 |
ProteomicsThe aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
The activity of 5’-adenosine monophosphate-activated protein kinase (AMPK) is inversely correlated with the cellular availability of glucose. When glucose levels are low, the glycolytic enzyme aldolase is not bound to fructose-1,6-bisphosphate (FBP) and, instead, signals to activate lysosomal AMPK. ...
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-10 | PXD035968 |
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