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CD73 (ecto-5'-nucleotidase) is a metabolic immune checkpoint that dephosphorylates AMP to produce adenosine. Adenosine plays a pivotal role in immunosuppressive tumor microenvironment (TME) through adenosine receptors expressed on various immune cells. AB680, a specific CD73 inhibitor, is currently ...
2025-08-04 | MTBLS11084 | MetaboLights
Dark teas are prepared by a microbial fermentation process. Flavan-3-ol B-ring fission analogues (FBRFAs) are some of the key bioactive constituents that characterise dark teas. The microbes and biosynthetic precursors involved in the formation of FBRFAs are not known. Using a unique solid-state fer...
ORGANISM(S): Trametes Hirsuta (ncbitaxon:5327) Cladosporium Sp. (ncbitaxon:1707700) Cladosporium Tenuissimum (ncbitaxon:70808) Aspergillus Niger (ncbitaxon:5061) Eurotium Cristatum (ncbitaxon:41421) Candida Metapsilosis (ncbitaxon:273372) Penicillium Steckii (ncbitaxon:303698) Penicillium Oxalicum (ncbitaxon:69781) Aspergillus Sp. (ncbitaxon:5065) Bjerkandera Adusta (ncbitaxon:5331) Aspergillus Ochraceus (ncbitaxon:40380) Penicillium Sp. (ncbitaxon:5081) 
2020-05-02 | MSV000085360 | GNPS
Mytilus coruscus are one of the dominant shellfish in the Yangtze estuary, but they often face food deprivation due to seasonal fluctuations in algal abundance caused by seasonal freshwater flushing and high-density aquaculture. To investigate the coping strategies of M. coruscus to starvation stres...
ORGANISM(S): Mytilus Coruscus 
2023-03-16 | PXD040908 |
Using patient derived lung cancer organoids to predict clinical response and find theraputic mechanisms
ORGANISM(S): Homo Sapiens 
2022-09-26 | PXD037076 |
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