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MetabolomicsMulti-omics association analysis reveals interactions between the oropharyngeal microbiome and the metabolome in pediatric patients with influenza A virus pneumonia.
Children are at high risk for influenza A virus (IAV) infections, which can develop into severe illnesses. However, little is known about interactions between the microbiome and respiratory tract metabolites and their impact on the development of IAV pneumonia in children. Using a combination of liq...
2024-09-25 | MTBLS4816 | MetaboLights
MetabolomicsLipidomic Changes in the Liver of Beagle Dogs Associated with Toxocara canis Infection

In this study, lipid alterations in Beagle dog’s liver caused by Toxocara canis infection were investigated by using liquid chromatography with tandem mass spectrometry at 12 hours post infection (hpi), 24 hpi and 36 days post infection (dpi). A total of 6 categories and 42 subclasses of...

2022-08-30 | MTBLS4015 | MetaboLights
UnknownA significant quantitative trait locus on chromosome Z and its impact on egg production traits in seven maternal lines of meat-type chicken.
Not available
S-EPMC9361671 | biostudies-literature
ProteomicsUbiquitin Ligase Enzyme FANCL Inhibits Peste des petits ruminants Virus Replication by Inducing Type I Interferon Production through Promoting Phosphorylation of TBK1
Peste des petits ruminants virus (PPRV) infection causes highly contagious and severe disease in domestic and wild ruminants. It is widely reported that PRRV infection causes considerable innate immunosuppression in its host and promotes viral replication. However, how does the host rescue the innat...
ORGANISM(S): Ovis aries 
2021-07-26 | PXD022271 | Pride
Peste des petits ruminants virus  quantitative proteomics  fancl  innate immune response  tbk1 
UnknownHuman viral encephalitis associated with suid herpesvirus 1.
Not available
S-EPMC8514202 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis pollen germination and tube growth
Pollen germination, along with pollen tube growth, is an essential process for the reproduction of flowering plants. The germinating pollen with tip-growth characteristics provides an ideal model system for the study of cell growth and morphogenesis. As an essential step towards a detailed underst...
ORGANISM(S): Arabidopsis thaliana 
2008-10-25 | E-GEOD-6696 | biostudies-arrayexpress
MetabolomicsGut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy
Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
2021-12-08 | MTBLS3174 | MetaboLights
MetabolomicsLung Lipidomic Alterations in Beagle Dogs Infected with Toxocara canis

Toxocariasis, mainly caused by Toxocara canis, and to a lesser extent, Toxocara cati, is a neglected parasitic zoonosis. The mechanisms that underlie the changes in lipid metabolism of T. canis infection in Beagle dogs' lungs remain unclear. Lipidomics is a rapidly emer...

2023-08-21 | MTBLS5583 | MetaboLights
ProteomicsAnalysis of pummelo proteome using iTRAQ
For protein identification, the following parameters were used. Peptide mass tolerance = 20 ppm, Missed cleavage = 2, MS/MS tolerance = 0.1 Da, Enzyme = Trypsin, Fixed modification: Carbamidomethyl (C), iTRAQ8plex(K), iTRAQ8plex(N-term), Variable modification：Oxidation(M)，Decoy database pattern=Reve...
ORGANISM(S): Citrus maxima (Pomelo) (Citrus grandis) 
2020-01-27 | PXD000527 | Pride
Itraq floral bud 
UnknownEfficacy and safety of a sequential treatment with clearing heat and eliminating phlegm and tonifying and activating blood circulation in treating acute ischemic stroke: study protocol for a randomized controlled trial.
Not available
S-EPMC9924680 | biostudies-literature
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