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TranscriptomicsCross-laboratory validation of the OncoScan FFPE Assay, a multiplex tool for whole genome tumour profiling
162 FFPE samples, representing six different tumour types, were profiled in triplicate across three independent laboratories. OncoScan¬ FFPE assay data was then analysed for reproducibility of genome-wide copy number, loss of heterozygosity and somatic mutations.
ORGANISM(S): Homo sapiens 
2015-02-18 | E-MTAB-2914 | biostudies-arrayexpress
TranscriptomicsIdentification of biomarkers that distinguish chemical contaminants using a gradient feature selection method
There are many toxic chemicals to contaminate the world and cause harm to human and other organisms. How to quickly discriminate these compounds and characterize their potential molecular mechanism and toxicity is essential. High through put transcriptomics profiles such as microarray have been prov...
ORGANISM(S): Rattus norvegicus 
2010-01-05 | E-GEOD-19662 | biostudies-arrayexpress
TranscriptomicsNext-generation sequencing and microarray-based interrogation of microRNAs from formalin-fixed, paraffin-embedded tissue: Assessment of cross-platform concordance.
We examine the concordance between miRNA-seq and cDNA-mediated annealing, selection, extension, and ligation (DASL) miRNA assays. We profiled two technically replicated FFPE specimens on both DASL and RNA-seq. This submission represents the RNA-seq component of study. The DASL samples used in the ...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-36147 | biostudies-arrayexpress
TranscriptomicsDifferentiation of NUT midline carcinoma by epigenomic reprogramming
Knockdown of the oncogene, BRD4-NUT, in a rare cancer, termed NUTmidline carcinoma (NMC), results in morphologic features consistent with squamous differentiation. Treatment with the HDAC-inhibitor, TSA, appears to cause the same phenotype. Here, we use gene expression profiling to compare the cha...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-18668 | biostudies-arrayexpress
Unknownp53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study.
Not available
S-EPMC10073933 | biostudies-literature
UnknownNo clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.
Not available
S-EPMC4630206 | biostudies-literature
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