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GenomicsE2F7 represses a transcriptional network of oscillating cell cycle genes to control S-phase progression.
E2F transcription factors are known to be important for timely activation of G1/S and G2/M genes required for cell cycle progression, but transcriptional mechanisms for deactivation of cell cycle regulated genes are unknown. Here, we show that E2F7 is highly expressed during mid to late S-phase, occ...
ORGANISM(S): Homo sapiens 
2012-01-04 | E-GEOD-32673 | biostudies-arrayexpress
TranscriptomicsMicroarray gene expression profiling in E2f7 and E2f8 deleted liver compared to control in mice
Two condition experiment were compared: Wild type vs. E2f7/8 dko mouse liver. Biological replicates: two wild type replicates and two E2f7/8 dko replicates for each of 3-wk, 4-wk and 16-wk age groups.
ORGANISM(S): Mus musculus 
2012-11-05 | E-MEXP-3384 | biostudies-arrayexpress
ProteomicsAssessment of Kinome-wide Rewiring Upon Picornavirus Infection
Picornaviridae is a large family of single-stranded positive RNA viruses that can infect both humans and animals. These include the enteroviruses (e.g. poliovirus, coxsackievirus and rhinoviruses) as well as the cardioviruses (e.g. encephalomyocarditis virus (EMCV)). Picornaviruses have evolved to i...
ORGANISM(S): Homo Sapiens 
2024-04-21 | PXD046598 | panorama
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