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TranscriptomicsLight-regulated genes in Cryptococcus neoformans
Light is a universal environmental signal perceived by many organisms, including the fungi in which light regulates both common and unique biological processes depending on the species. We conducted a whole-genome microarray analysis on the basidiomycete fungus Cryptococcus neoformans to identify li...
ORGANISM(S): Cryptococcus neoformans var. neoformans 
2010-04-23 | E-GEOD-21484 | biostudies-arrayexpress
Transcriptomics3' single cell sequencing of CD45+ lymphocytes sorted from mesenteric white adipose tissue in wildtype C57BL/6 and WIPf1-/- mice
Mesenteric white adipose tissue from wildtype C57BL/6 and Wipf1-/- mice was harvested through vivosection, minced and digested. Tissue-resident lymphocytes were enriched with Percoll gradient centrifugation. CD45 staining and fluorescence associated cell sorting were performed to achieve a pure lymp...
ORGANISM(S): Mus musculus 
2026-07-31 | E-MTAB-17384 | biostudies-arrayexpress
UnknownAntisense therapy in a rat model of Alexander disease reverses GFAP pathology, white matter deficits, and motor impairment.
Not available
S-EPMC8730534 | biostudies-literature
UnknownModeling Alexander disease with patient iPSCs reveals cellular and molecular pathology of astrocytes.
Not available
S-EPMC4940830 | biostudies-literature
Genomics
Targeting white matter astrocytes with a Gfap-disruptive Cas9 nuclease benefits a murine model of Alexander disease
PRJNA1484821 | ENA
UnknownGFAP mutation and astrocyte dysfunction lead to a neurodegenerative profile with impaired synaptic plasticity and cognitive deficits in a rat model of Alexander disease.
Not available
S-EPMC11936449 | biostudies-literature
UnknownQuantitative diffusion imaging and genotype-by-sex interactions in a rat model of Alexander disease.
Not available
S-EPMC10842025 | biostudies-literature
UnknownDescription of the Hamburg Alexander Leukodystrophy Cohort-Insights into Practical Classification and the Care Situation.
Not available
S-EPMC12524457 | biostudies-literature
TranscriptomicsWhite-Opaque Switching in Natural MTLa/alpha Isolates of Candida albicans: Evolutionary Implications for Roles in Host Adaptation, Pathogenesis and Sex
The discovery of white-opaque switching in natural MTLa/alpha isolates of Candida albicans sheds new light on the evolution of phenotypic plasticity and host adaptation. Comparing gene expression of white and opaque cells of a MTL a/alpha strain
ORGANISM(S): Candida albicans 
2013-04-01 | E-GEOD-43938 | biostudies-arrayexpress
TranscriptomicsGene expression data from iPSC-derived astrocytes, comparison
Alexander disease (AxD) is a fatal neurological illness characterized by white-matter degeneration and formation of Rosenthal fibers, which contain glial fibrillary acidic protein (GFAP) as astrocytic inclusion. AxD is mainly caused by a gene mutation encoding GFAP, although the underlying pathomech...
ORGANISM(S): Homo sapiens 
2016-09-30 | GSE83374 | GEO
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