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TranscriptomicsMaternal inhalation of surface-coated nano-sized titanium dioxide (UV-Titan): Effects in prenatally exposed offspring on hepatic DNA damage and gene expression
In the present study we investigate the effect of maternal pulmonary exposure to titanium dioxide (UV-Titan designed for use in the paint and lacquer industry) on prenatally exposed offspring. Time-mated mice (C57BL/6BomTac) were exposed by inhalation for 1 h/day to 42 mg UV-titan/m3 aerosolized pow...
ORGANISM(S): Mus musculus 
2012-03-19 | E-GEOD-29067 | biostudies-arrayexpress
MetabolomicsLongitudinal multi-omics reveals subset-specific mechanisms underlying irritable bowel syndrome

The gut microbiome has been implicated in multiple human chronic gastrointestinal (GI) disorders. Determining its mechanistic role in disease has been difficult due to apparent disconnects between animal and human studies and lack of an integrated multi-omics view of disease-specific physiologica...

2020-09-08 | MTBLS1396 | MetaboLights
ProteomicsPputida - Whole organism, NSAF (Lidburyetal,environmicrobiol,2016)
abundance based on NSAF, Interaction consistency score: 12.3, Coverage: 38
ORGANISM(S): 160488 
2016-00-00 | 1991256584 | PAXDB
UnknownMedicare Advantage Plan Double Bonuses Drive Racial Disparity In Payments, Yield No Quality Or Enrollment Improvements.
Not available
S-EPMC9278554 | biostudies-literature
GenomicsUnusual DNA packaging characteristics in endo-reduplicated C. elegans oocytes defined by in vivo accessibility to an endogenous nuclease activity
We describe DNA-surface interactions in activated C. elegans oocytes that are revealed through the activity of an endogenous nuclease. Our analysis began with an unexpected observation that a majority (>50%) of DNA from C. elegans fer-1 oocytes can be recovered in fragments of ~500 base pairs or sh...
ORGANISM(S): Caenorhabditis elegans 
2013-07-01 | E-GEOD-46499 | biostudies-arrayexpress
TranscriptomicsExpression data from human brain tumors and human normal brain
The characteristics of immune cells infiltrating pediatric brain tumors is largely unexplored. A better understanding of these characteristics will provide a foundation for development of immunotherapy for pediatric brain tumors. Gene expression profiles were used to identify immune marker gene that...
ORGANISM(S): Homo sapiens 
2013-08-25 | E-GEOD-50161 | biostudies-arrayexpress
ProteomicsTandem Mass Tag-Based Quantitative Proteomic Profiling Identifies Novel Serum Biomarkers of Drug-Induced Liver Injury in Humans
Diagnosis of drug-induced liver injury (DILI) and its distinction from other liver diseases are significant challenges in drug development and clinical practice. In this study we identify, confirm, and replicate the biomarker performance characteristics of candidate proteins in a cohort of patients ...
ORGANISM(S): Homo Sapiens 
2024-01-04 | PXD034882 | panorama
MetabolomicsThe phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 inhibitor 3PO is a modulator of neutrophil metabolism, ROS production and NET release
Neutrophils are key effector leukocytes of the innate immune system and play a pivotal role in defending the host against microbial infections. Recent studies have identified a crucial link between glycolysis and neutrophil cellular functions. We have investigated in human neutrophils, the intricate...
2025-08-14 | MTBLS6215 | MetaboLights
UnknownA combined DHA-rich fish oil and cocoa flavanols intervention does not improve cognition or brain structure in older adults with memory complaints: results from the CANN randomized, controlled parallel-design study.
Not available
S-EPMC10447509 | biostudies-literature
UnknownTumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis.
Not available
S-EPMC9169934 | biostudies-literature
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