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TranscriptomicsPig Longissimus muscle: comparison between Basque and Large White breeds
Transcriptional profiling of pig skeletal muscle comparing two divergent breeds: Large white (LW, conventional) and Basque (B, local, indigeneous). Two-condition experiment, LW vs. B muscles. Biological replicates: 20 B and 20 LW. One replicate per array.
ORGANISM(S): Sus scrofa 
2012-11-20 | E-GEOD-26614 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of blood cells from hypertriglyceridemic men treated with docosahexaenoic acid shows suppression of LDLR and OLR1 gene expression.
Previously published results from our double-blind, placebo-controlled parallel study with docosahexaenoic acid (DHA) supplementation (3 g/d, 90 d) to hypertriglyceridemic men (39-66yr) showed that DHA reduced several risk factors for cardiovascular disease (CVD), including the plasma concentration ...
ORGANISM(S): Homo sapiens 
2010-02-21 | E-GEOD-20114 | biostudies-arrayexpress
TranscriptomicsIdentification of the 3' end of the pig miRNA by the RAKE technology [platform 1: 9003467]
We applied a new computational approach to predict specie-specific and conserved miRNAs, than experimentally confirmed by a modified RNA-primed Array-based Klenow Extension (RAKE) method. We identified 489 conserved and 1,178 pig-specific novel miRNAs increasing our tally of confirmed miRNAs to 1,66...
ORGANISM(S): Sus scrofa 
2014-03-31 | E-GEOD-28137 | biostudies-arrayexpress
TranscriptomicsIdentification of the 3' end of the pig miRNA by the RAKE technology [platform 2: 9003179]
We applied a new computational approach to predict specie-specific and conserved miRNAs, than experimentally confirmed by a modified RNA-primed Array-based Klenow Extension (RAKE) method. We identified 489 conserved and 1,178 pig-specific novel miRNAs increasing our tally of confirmed miRNAs to 1,66...
ORGANISM(S): Sus scrofa 
2014-03-31 | E-GEOD-28138 | biostudies-arrayexpress
TranscriptomicsIdentification of responsive probes for mRNA transcripts of the pig (S. scrofa) genome
Pig mRNAs Ensembl transcripts (Ver. 56) and UniGene (Ver. 38) sequences were used to produce a dedicated microarray platform to analyze mRNAs gene expression. Based on sequence similarity we rejected UniGene features that overlapped more than 40% with an Ensembl transcript. After this filter we obta...
ORGANISM(S): Sus scrofa 
2014-03-31 | E-GEOD-28636 | biostudies-arrayexpress
TranscriptomicsProfiling circulating microRNA expression in a mouse model of nerve allotransplantation (part 2)
Background. The lack of noninvasive biomarkers of rejection remains a challenge in the accurate monitoring of deeply buried nerve allografts and precludes optimization of therapeutic intervention. This study aimed to establish the expression profile of circulating microRNAs (miRNAs) during nerve all...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-48971 | biostudies-arrayexpress
TranscriptomicsProfiling circulating microRNA expression in a mouse model of nerve allotransplantation (part 1)
Background. The lack of noninvasive biomarkers of rejection remains a challenge in the accurate monitoring of deeply buried nerve allografts and precludes optimization of therapeutic intervention. This study aimed to establish the expression profile of circulating microRNAs (miRNAs) during nerve all...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-48969 | biostudies-arrayexpress
TranscriptomicsGlobal hepatic gene expression in rainbow trout exposed to sewage effluents
Effluents from sewage treatment plants contain a mixture of micropollutants with the potential of harming aquatic organisms. Thus, addition of advanced treatment techniques to complement existing conventional methods has been proposed. Some of the advanced techniques could, however, potentially prod...
ORGANISM(S): Oncorhynchus mykiss 
2012-05-09 | E-GEOD-37574 | biostudies-arrayexpress
TranscriptomicsMessenger RNA transcript expression in the pig (S. scrofa)
90K Combimatrix gene expression microarrays were composed by 17,048 replicated probes and 963 not replicated specific for the Ensembl (Ver. 56) Transcripts (protein coding + pseudogenes + retrotransposed elements), 11,363 replicated probes specific for the UniGene clusters (Ver. 38) of length compri...
ORGANISM(S): Sus scrofa 
2014-03-31 | E-GEOD-27853 | biostudies-arrayexpress
TranscriptomicsDrosophila Ecdysone Receptor Study
We used the DamID method to systematically identify the binding sites of Ecdysone Receptor and its heterodimeric partner USP across the whole genome in Drosophila Kc cells. We find that the EcR sites are a subset of the USP sites and that only a proportion are ecdysone regulated from an accompanying...
ORGANISM(S): Drosophila melanogaster 
2008-05-01 | E-GEOD-9156 | biostudies-arrayexpress
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