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TranscriptomicsscRNA-seq of stromal vascular cells from 48 week (aged) mouse subcutaneous adipose tissue compared to control 10 week (young) mouse SVF
Adipose tissue mass and adiposity change throughout the lifespan. During aging, while visceral adipose tissue (VAT) tends to increase, peripheral subcutaneous adipose tissue (SAT) decreases significantly. Unlike VAT, which is linked to metabolic diseases, SAT has beneficial effects. However, the mol...
ORGANISM(S): Mus musculus 
2021-03-25 | E-MTAB-10221 | biostudies-arrayexpress
TranscriptomicsTranscriptome Remodeling Associated with Chronological Aging in the Dinoflagellate, Karenia brevis
To gain an understanding of processes that underlie chronological aging in this dinoflagellate, a microarray study was carried out to identify changes in the global transcriptome that accompany the entry and maintenance of stationary phase up to the onset of cell death. The transcriptome of K. brevi...
ORGANISM(S): Karenia brevis 
2012-01-01 | E-GEOD-31913 | biostudies-arrayexpress
TranscriptomicsGlobal Analysis of mRNA Half-lives Following Biosynthetic Labeling in a Dinoflagellate, Karenia brevis
Dinoflagellates possess many physiological processes that appear to be under post-transcriptional control. However, the extent to which their genes are regulated post-transcriptionally remains unresolved. To gain insight into the role of differential mRNA stability in dinoflagellates, we biosynthe...
ORGANISM(S): Karenia brevis 
2013-08-01 | E-GEOD-46174 | biostudies-arrayexpress
TranscriptomicsGlobal Analysis of de novo Transcription Following Biosynthetic Labeling in a Dinoflagellate, Karenia brevis
Dinoflagellates possess many physiological processes that appear to be under post-transcriptional control. However, the extent to which their genes are regulated post-transcriptionally remains unresolved. To gain insight into role of de novo transcription in dinoflagellates, we biosynthetically la...
ORGANISM(S): Karenia brevis 
2013-08-01 | E-GEOD-46175 | biostudies-arrayexpress
TranscriptomicsTranscriptional Responses of Karenia brevis to Acute Stresses
Dinoflagellates have evolved a nuclear organization unlike that of any other eukaryotic group. Recent studies find a predominance of post-transcriptional control of dinoflagellate gene expression. This study investigated regulation of the environmental stress response in the red tide dinoflagellat...
ORGANISM(S): Karenia brevis 
2010-12-01 | E-GEOD-13961 | biostudies-arrayexpress
UnknownIndependent replication and meta analysis of association studies establish TNFSF4 as a susceptibility gene preferentially associated with the subset of anticentromere-positive patients with systemic sclerosis.
Not available
S-EPMC3687343 | biostudies-literature
TranscriptomicsChip-chip from Escherichia coli MG1655 K-12, WT and M-bM-^HM-^Ffnr strains
Mapping the occupancy of FNR, HNS, and IHF throughout the genome of Escherchia coli MG1655 K-12 using an affinity purified antibody under anerobic growth conditions. We also mapped the binding of the M-CM-^_ subunit of RNA Polymerase under both aerobic and anaerobic growth conditions. As a control, ...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2013-06-20 | E-GEOD-41186 | biostudies-arrayexpress
GenomicsGenome-wide analysis of FNR and M-OM-^C70 in E. coli under aerobic and anaerobic growth conditions.
We found many binding sites for FNR under glucose fermentative anaerobic growth conditions. Also, many binding sites were identified for M-OM-^C70 under both aerobic and anaerobic growthin conditions. Descirbed in the manuscript "Genome-scale Analysis of E. coli FNR Reveals the Complexity of B...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2013-06-20 | E-GEOD-41187 | biostudies-arrayexpress
UnknownAssociation of Baseline Factors With Glycemic Outcomes in GRADE: A Comparative Effectiveness Randomized Clinical Trial.
Not available
S-EPMC10973909 | biostudies-literature
TranscriptomicsGenetic characterization of tumor-stage mycosis fungoides
Mycosis fungoides patients who develop tumors or extracutaneous involvement usually have a poor prognosis with no curative therapy available so far. In the present EORTC multicenter study, the genomic profile of 41 skin biopsies from tumor-stage mycosis fungoides was analyzed using a high-resolution...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-18098 | biostudies-arrayexpress
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