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TranscriptomicsTranscription profiling of human peripheral blood leukocytes from CHASRS particpants
Gene expression profiling was carried out on peripheral blood leukocytes from 14 healthy older adults. The primary research question is whether gene expression differs in individuals experiencing chronically high levels of social isolation (by UCLA Loneliness Scale) vs chronically low levels of soc...
ORGANISM(S): Homo sapiens 
2009-04-23 | E-GEOD-7148 | biostudies-arrayexpress
TranscriptomicsNck2 Regulates Adiposity and Adiposity-Related Metabolic Disorders in Mice and Human
Obesity is linked to the development of metabolic disorders. Expansion of white adipose tissue (WAT) from hypertrophy of pre-existing adipocytes and/or differentiation of precursors into new mature adipocytes contributes to obesity. We found that Nck2 expression is largely restricted to WAT, raising...
ORGANISM(S): Mus musculus 
2016-07-01 | E-GEOD-63510 | biostudies-arrayexpress
TranscriptomicsIllumina Infinium HumanMethylationEPIC DNA methylation microarray of human donor whole-blood from patients with and without Age-related Macular Degeneration
DNA methylation microarray analysis was performed on human donor whole blood samples from patients with and without AMD. A total of 30 patient samples including 16 Normal, 3 AREDS grade 2 (early AMD) and 11 AREDS grade 3 (intermediate AMD) (AMD total, n = 14) were selected. Samples were obtained fro...
ORGANISM(S): Homo sapiens 
2021-12-31 | E-MTAB-11279 | biostudies-arrayexpress
UnknownMolecular and phylogenetic characterization of the homoeologous EPSP Synthase genes of allohexaploid wheat, Triticum aestivum (L.).
Not available
S-EPMC4619226 | biostudies-literature
TranscriptomicsTranscription profiling of human lymphatic endothelial cells, mouse dermal cells and human skin cells reveals an inflammation-induced mechanism for leukocyte transmigration of lymphatic vessel endothelium.
The exit of antigen-presenting cells (APC) and lymphocytes from inflamed skin to afferent lymph is vital for the initiation and maintenance of dermal immune responses. How such exit is achieved and how cells transmigrate the distinct endothelium of lymphatic vessels is however unknown. Here we show ...
ORGANISM(S): Homo sapiens 
2008-11-07 | E-GEOD-6257 | biostudies-arrayexpress
TranscriptomicsWhole blood mRNA transcription profiling of host immune changes in neonatal sepsis during vancomycin therapy
The purpose of this study was to investigate changes in host gene expression profiles of neonatal infants with sepsis prior to the initiation of and during vancomycin therapy, to identify treatment-responsive genes and signature pathways associated with recovery from neonatal sepsis. The study analy...
ORGANISM(S): Homo sapiens 
2025-11-25 | E-MTAB-15687 | biostudies-arrayexpress
UnknownPlay ontogeny in young chickens is affected by domestication and early stress.
Not available
S-EPMC9363459 | biostudies-literature
MetabolomicsAzithromycin promotes relapse by disrupting immune and metabolic networks after allogeneic stem cell transplantation
Administration of azithromycin after allogeneic hematopoietic stem cell transplantation for hematological malignancies has been associated with relapse in a randomized phase 3 controlled clinical trial. Studying 240 samples from patients randomized in this trial is a unique opportunity to better und...
2022-08-22 | MTBLS406 | MetaboLights
TranscriptomicsRNA-seq of three Spodoptera frugiperda tissues (Midgut, Fat body, Hemocytes), at 2 time-points (8h and 15h) after infestation by entomopathogenic nematodes Steinernema carpocapsae/Xenorhabdus nematophila
Nematodes such as Steinernema carpocapsae are used as organic pesticides because of their ability to prey on live insects. They do so thanks to their symbiotic bacteria, that they release within the hemocoel of insects. In this study we wanted to study how Spodoptera frugiperda, a Lepidoptera pest o...
ORGANISM(S): Spodoptera frugiperda 
2019-12-03 | E-MTAB-7976 | biostudies-arrayexpress
TranscriptomicsVIB1, a link between glucose signaling and carbon catabolite repression, is essential for plant cell wall degradation by Neurospora crassa
Purpose: To explore the function of VIB1 in regulating cellulase production in Neurospora crassa. Method: mRNA from vib-1 mutants were collected after a culture shift from sucrose to Avicel (crystaline cellulose) or carbon-free media. Expression profiles of vib-1 mutants were compared with published...
ORGANISM(S): Neurospora crassa 
2014-07-08 | E-GEOD-52316 | biostudies-arrayexpress
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