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TranscriptomicsExpression data from human brain samples
Spontaneous intracerebral hemorrhage (ICH) represents about 15% of all strokes and is associated with high mortality rates. Our aim was to identify the gene expression changes and biological pathways altered in the brain following ICH. Twelve brain samples were obtained from four deceased patients w...
ORGANISM(S): Homo sapiens 
2010-09-23 | E-GEOD-24265 | biostudies-arrayexpress
ProteomicsProteomic analysis of extracellular vesicles and conditioned medium from human Adipose-derived Stem/Stromal Cells and Dermal Fibroblasts
Conditioned medium (CM) and extracellular vesicles (EV) from human Adipose-derived Stem/stromal cells (ASC) and Dermal fibroblasts (DF) can represent valid cell substitutes in regenerative medicine and other therapeutic applications. Whether one of the two cell products should be preferred over the ...
ORGANISM(S): Homo sapiens (Human) 
2020-12-23 | PXD020219 | Pride
Adipose-derived stromal cells Label-free quantitative proteomics Extracellular vesicles Dermal fibroblasts Conditioned medium Secretome 
GenomicsGCAT | Genomes for life: cohort study of the genomes of Catalonia
The GCAT Study have recruited 20 000 participants aged 40–65 years. Participants who agreed to take part in the study completed a self-administered computer-driven questionnaire, and underwent blood pressure, cardiac frequency and anthropometry measurements. For each participant, blood plasma, ...
EGAS00001003018 | EGA
TranscriptomicsRibosome profiling of Mycobacterium tuberculosis under nutrient starvation
We have performed parallel ribosome profiling and RNA sequencing to determine which mRNAs are being translated during exponential growth and following 24 hours of nutrient starvation in the human pathogen Mycobacterium tuberculosis.
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2021-02-02 | E-MTAB-8835 | biostudies-arrayexpress
TranscriptomicsExpression data from WT Col-0 and the pdx1.3 ko mutant of Arabidopsis
We performed a microarray experiment to assess the global changes in transcription occurring in leaves and roots of the vitamin B6 deficient pdx1.3 knockout mutant in comparison to WT. Vitamin B6 (pyridoxal 5′-phosphate) is an essential cofactor of many metabolic enzymes. Plants biosynthesize the vi...
ORGANISM(S): Arabidopsis thaliana 
2015-07-25 | E-GEOD-71312 | biostudies-arrayexpress
TranscriptomicsTime-resolved immune dynamics in rheumatoid arthritis under methotrexate therapy
Methotrexate (MTX) serves as the primary treatment for rheumatoid arthritis (RA), though its mechanism of action is not yet fully understood. The goal of this study was to map the cellular and molecular changes triggered by MTX across different points in time. Using a prospective longitudinal design...
ORGANISM(S): Homo sapiens 
2026-07-01 | E-MTAB-17153 | biostudies-arrayexpress
TranscriptomicsOverexpression of USF1 in HEK293T cells
Overexpression of USF1 in HEK293T cells in vitro to ascertain the genes downstream of USF1. Will identify direct targets as well as indirect targets of USF1. Keywords: Overexpression of transcription factor to determine downstream targets. Cloned USF1 from cDNA and transiently transfected into HEK2...
ORGANISM(S): Homo sapiens 
2009-09-14 | E-GEOD-17300 | biostudies-arrayexpress
Genomics246a7055-8319-4940-900a-135fa7ecf419 - samples
Disease diagnoses of GCAT Cohort participants obtained from electronic health records (EHR), mainly including the time period from 2012 to 2017. Disease diagnoses are codified in ICD-9, and the position of diagnosis refers to primary/secondary diagnoses (up to 14 secondary diagnoses per visit). The ...
EGAD00001007731 | EGA
TranscriptomicsTranscription profiling by array of mouse wild type and Nkx2.2 knock-out embryos
The goal: Investigate the genes differentlly expressed during pancreas development. The model: The Nkx2.2 null allele was generated using standard homologous recombination in ES cells. The Pgk:NeoR cassette was inserted into a 4.4 Kb deletion of the Nkx2.2 genomic locus, effectively deleting bot...
ORGANISM(S): Mus musculus 
2011-08-27 | E-MTAB-356 | biostudies-arrayexpress
GenomicsGCATcoreSpain V1
4988 samples issued from GCAT cohort, genotyped with MEGAex-Infinium Array, with data for Cr1-22. Plink files with QC but not imputed.
EGAD00010001665 | EGA
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