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MetabolomicsUnexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood fraction)
Metabolomics, a new branch of chemical biology, provides compositional and quantitative information about the state of organism or cell at the levels of metabolite constituents. We here report non-targeted metabolome of human blood that is made up of plasma and red blood cells (RBCs), using liquid-c...
2014-07-08 | MTBLS87 | MetaboLights
MetabolomicsUnexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites (Blood plasma and RBC fractions)
Metabolomics, a new branch of chemical biology, provides compositional and quantitative information about the state of organism or cell at the levels of metabolite constituents. We here report non-targeted metabolome of human blood that is made up of plasma and red blood cells (RBCs), using liquid-c...
2014-07-08 | MTBLS88 | MetaboLights
TranscriptomicsTranscription profiling of white blood cells from human males before and after exercise to determine the effect of acute exercise on gene expression profiles inwhite blood cells and to identify genes for use as markers for monitoring exercise and training load
White blood cells (WBCs) express tens of thousands of genes. Their expression levels are modified by genetic and external factors. The purpose of the present study was to investigate the effects of acute exercise on gene expression profiles (GEPs) of WBCs and to identify suitable genes which may ser...
ORGANISM(S): Homo sapiens 
2007-10-27 | E-GEOD-3606 | biostudies-arrayexpress
MetabolomicsHypothalamic SLC7A14 accounts for aging-reduced lipolysis in white adipose tissue

The central nervous system has been implicated in the age-induced reduction in adipose tissue lipolysis. SLC7A14 is a lysosomal membrane protein highly expressed in the brain. Herein, we investigated the possible role of hypothalamic SLC7A14 in the age-induced lipolysis reduction. In this study, ...

2024-07-23 | MTBLS9872 | MetaboLights
TranscriptomicsTranscriptional profiling of human white blood cells at the different stages of NYHA classification
Human white blood cells from healthy, heart failure risk patients, asymptomatic left ventricular dysfunction patients, chronic heart failure, acute heart failure patients Common reference experiment, 9 replicates per group.
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-21125 | biostudies-arrayexpress
GenomicsConserved DNA methylation patterns in healthy blood cells and extensive changes in leukemia measured by a new quantitative technique.
We describe a simple method, Digital Restriction Enzyme Analysis of Methylation (DREAM), based on sequential DNA digestion with a pair of methylation-blocked and methylation-tolerant neoschizomeric restriction enzymes SmaI/XmaI followed by end repair and ultra-deep sequencing. DREAM provides informa...
ORGANISM(S): Homo sapiens 
2012-11-08 | E-GEOD-39787 | biostudies-arrayexpress
MetabolomicsMulti-Omics profiling reveals immunometabolic adaptations underlying disease resilience in indigenous Lueyang Silky Fowl compared to White Leghorns
Sustainable avian production demands genetic strategies beyond vaccines to enhance disease resilience, particularly in indigenous breeds like Lueyang Silky Fowl (LSF), which show superior resistance compared to commercial White Leghorn chickens (WLC) but lack molecular characterization. We hypothesi...
2026-05-27 | MTBLS14590 | MetaboLights
TranscriptomicsWhite Cells Facilitate Opposite- and Same-Sex Mating of Opaque Cells in Candida albicans
Modes of sexual reproduction in eukaryotic organisms are highly diversified. The human fungal pathogen Candida albicans undergoes a phenotypic switch from the white to the opaque phase in order to become mating-competent. In this study, we report that functionally and morphologically differentiated ...
ORGANISM(S): Candida albicans 
2014-10-23 | E-GEOD-56039 | biostudies-arrayexpress
TranscriptomicsOrigin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp - single cell RNAseq dataset 1
Splenic white pulp (WP) structures are underpinned by fibroblastic stromal cells (FSCs) to facilitate splenic compartmentalization and execute efficient immune responses. Although distinct WP FSCs exhibit various molecular traits, the origin and the hierarchical differentiation of different cell sub...
ORGANISM(S): Mus musculus 
2019-03-27 | E-MTAB-7094 | biostudies-arrayexpress
GenomicsBulk White Blood Cells in MAFLD/MASH
Bulk White Blood Cells in MAFLD/MASH
PRJNA1109377 | ENA
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