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TranscriptomicsHIF-1synergizes with glucocorticoids to promote BFU-E progenitor self-renewal
With the aim of finding small molecules that stimulate erythropoiesis earlier than erythropoietin and that enhance CFU-E production, we studied the mechanism by which glucocorticoids increase CFU-E formation. Using BFU-E and CFU-E progenitors purified by a new technique, we demonstrate that glucocor...
ORGANISM(S): Mus musculus 
2010-12-21 | E-GEOD-26086 | biostudies-arrayexpress
UnknownAvian W and mammalian Y chromosomes convergently retained dosage-sensitive regulators.
Not available
S-EPMC5359078 | biostudies-literature
ProteomicsThermal proteome profiling of stationary-phase E. coli treated with semapimod
There is a need to discover and develop non-toxic antibiotics that are effective against metabolically dormant bacteria, which underlie chronic infections and promote antibiotic resistance. Traditional antibiotic discovery has historically favored compounds effective against actively metabolizing ce...
ORGANISM(S): Escherichia coli 
2023-08-21 | PXD044230 | Pride
Ms-cetsa Thermal proteome profiling Drug discovery Tpp Cetsa Thermal profiling 
TranscriptomicsHalobacterium NRC-1 Diurnal experiment Dark 3
The wild type strain of Halobacterium salinarium strain NRC-1 was used for the diel growth experiments. Culturing from colony was done under constant light in a liquid Complete Medium (CM; at 37 ºC with shaking at 220 rpm). For experiment, cultures were started at an OD = 0.005. Cultures were gr...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-27 | E-GEOD-7711 | biostudies-arrayexpress
TranscriptomicsHalobacterium NRC-1 Diurnal experiment Dark 2
The wild type strain of Halobacterium salinarium strain NRC-1 was used for the diel growth experiments. Culturing from colony was done in a liquid Complete Medium (CM; at 42 ºC with shaking at 100 rpm). For experiment, cultures were started at an OD >> 0.001. Cultures were grown aerobically (sha...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-27 | E-GEOD-7710 | biostudies-arrayexpress
TranscriptomicsHalobacterium NRC-1 Diurnal experiment Light 2
The wild type strain of Halobacterium salinarium strain NRC-1 was used for the diel growth experiments. For experiment, cultures were started at an OD >> 0.001. Cultures were grown anaerobically at a temperature of 38° C under light:dark cycles (12:12 hrs) for 120 hours then grown under constant ...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-27 | E-GEOD-7712 | biostudies-arrayexpress
UnknownKIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C.
Not available
S-EPMC12834474 | biostudies-literature
GenomicsWhole-genome nucleosome mapping in meiotic diploid S. cerevisiae
We determined nucleosome positions throughout the genome in diploid S. cerevisiae undergoing early stages of synchronous meiosis. This study sought to assess if systematic reorganization of nucleosomes occurs during meiotic prophase at or near sites of DNA double strand break formation. Six samples ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-07 | E-GEOD-26452 | biostudies-arrayexpress
TranscriptomicsFlag Chromatin IP in Cyclin D1 Flag-HA tagged E.14.5 embryos versus Flag Chromatin IP in wildtype E.14.5 embryos
Cyclin D1 belongs to the core cell cycle machinery1, and it is frequently overexpressed in human cancers2. The full repertoire of cyclin D1 functions in normal development and in cancer cells is currently unknown. To address this question, here we introduce a novel approach that allows one to deter...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-13632 | biostudies-arrayexpress
TranscriptomicsHalobacterium NRC-1 oxygen, light and ura3 perturbation
A 50ml culture of Halobacterium NRC-1 knockout strain delta-ura3 was grown to mid-log phase in a 125ml flask in rich media under varying oxygen and light conditions. Low and high light indicate growth in a painted flask versus growth in a standard clear flask under constant standard incubator illu...
ORGANISM(S): Halobacterium sp. NRC-1 
2010-05-26 | E-GEOD-7715 | biostudies-arrayexpress
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