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ProteomicsProteomics Analysis of Lymphoblastoid Cell lines from Patients with Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) consists in the progressive degeneration of motor neurons, caused by mechanisms that are poorly understood and for which there is no cure. Some of the cellular perturbations associated with ALS can be detected in peripheral cells, including lym-phocytes from blood...
ORGANISM(S): Homo sapiens (Human) 
2023-03-12 | PXD040240 | Pride
Amyotopphic lateral sclerosis  proteomics  mass spectrometry  biomarkers 
ProteomicsProteomics analysis of human breast milk by two-dimensional polyacrylamide gel electrophoressi (2D-PAGE) coupled with mass spectrometry to assess breast cancer risk
Breast Cancer (BC) is one of the most common cancers and one of the most common causes for cancer- related mortality. Discovery of protein biomarkers associated with cancer, is considered as important for early diagnosis and prediction of the cancer risk. Protein biomarkers could be investigated by ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-20 | PXD040188 | Pride
Breast cancer  breast milk  biomarkers  protein dysregulation  2d-page  proteomics  mass spec-trometry 
Proteomics2D-PAGE coupled with nLC-MS/MS-based identification of differentialy expressed proteins and tumorigenic pathways in MCF7 breast cancer cell line transfected for JTB protein silencing
Identification of new cancer-associated genes/proteins, characterization of their expression vari-ation, the interactomics-based assessment of differentially expressed genes/proteins (DEGs/DEPs), and understanding the tumorigenic pathways and biological processes involved in BC genesis and progressi...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046265 | Pride
Breast cancer (bc)  mcf7  jtb protein silencing  overexpressed jtb-interactome  downregulated jtb-interactome  tumorigenic pathways 
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