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MetabolomicsA polyamine-centric blood-based metabolite panel predictive of poor response to CAR T-cell therapy in large B cell lymphoma

Anti-CD19 chimeric antigen receptor (CAR) T-cell therapy for relapsed or refractory (r/r) large B-cell lymphoma (LBCL) results in durable response in only a subset of patients. MYC overexpression in LBCL tumors is associated with poor response to treatment. We tested whether a MYC-driven polyamin...

2022-10-31 | MTBLS5381 | MetaboLights
UnknownSmall espin: a third actin-bundling protein and potential forked protein ortholog in brush border microvilli.
Not available
S-EPMC2132824 | biostudies-literature
UnknownLenalidomide and rituximab for the initial treatment of patients with chronic lymphocytic leukemia: a multicenter clinical-translational study from the chronic lymphocytic leukemia research consortium.
Not available
S-EPMC4067945 | biostudies-literature
UnknownPreclinical combination of TP-0903, an AXL inhibitor and B-PAC-1, a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia.
Not available
S-EPMC4963009 | biostudies-literature
UnknownTwo-year follow-up of KTE-X19 in patients with relapsed or refractory adult B-cell acute lymphoblastic leukemia in ZUMA-3 and its contextualization with SCHOLAR-3, an external historical control study.
Not available
S-EPMC9734710 | biostudies-literature
UnknownPhase I First-in-Human Study of Venetoclax in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma.
Not available
S-EPMC5455685 | biostudies-literature
UnknownEfficacy and safety in a 4-year follow-up of the ELEVATE-TN study comparing acalabrutinib with or without obinutuzumab versus obinutuzumab plus chlorambucil in treatment-naive chronic lymphocytic leukemia.
Not available
S-EPMC8979808 | biostudies-literature
UnknownProteomics profiling identifies induction of caveolin-1 in chronic lymphocytic leukemia cells by bone marrow stromal cells.
Not available
S-EPMC5882591 | biostudies-literature
UnknownCombination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cells.
Not available
S-EPMC4814351 | biostudies-literature
TranscriptomicsTranscription profiling by array of human B cells from patients with chronic lymphocytic leukemia after co-culture with nurse-like cells
In the marrow and lymphatic tissues, chronic lymphocytic leukemia (CLL) cells interact with accessory cells that constitute the leukemia microenvironment. In lymphatic tissues, CLL cells are interspersed with CD68+ nurselike cells (NLC) and T cells. However, the mechanism regulating co-localization ...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-13811 | biostudies-arrayexpress
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