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UnknownPolymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus.

Background & aims

Barrett's esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). We found the risk to be BE has been associated with single nucleotide polymorphisms (SNPs) on chromosome 6p21 (within the HLA region) and on 16q23, where the closest protein-coding gene is FOXF1...
S-EPMC4315134 | biostudies-literature
UnknownNormal inflammatory markers and acute appendicitis: a national multicentre prospective cohort analysis.

Purpose

For the diagnosis of acute appendicitis, the combination of clinical and laboratory variables achieves high diagnostic accuracy. Nevertheless, appendicitis can present with normal laboratory tests of inflammation. The aim of this study was to investigate the incidence of normal infla...
S-EPMC8195794 | biostudies-literature
UnknownAccuracy of imaging in discriminating complicated from uncomplicated appendicitis in daily clinical practice.

Background

Radiologic imaging can accurately diagnose acute appendicitis, but little is known about its discriminatory capacity between complicated and uncomplicated appendicitis.

Objective

This study aims to investigate the accuracy of imaging in discriminating complicated from uncom...
S-EPMC9167165 | biostudies-literature
UnknownManagement of paraesophageal hiatus hernia: recommendations following a European expert Delphi consensus.

Aims

There is considerable controversy regarding optimal management of patients with paraesophageal hiatus hernia (pHH). This survey aims at identifying recommended strategies for work-up, surgical therapy, and postoperative follow-up using Delphi methodology.

Methods

We conducted a 2...
S-EPMC10234895 | biostudies-literature
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