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TranscriptomicsA genome-wide longitudinal transcriptome analysis of the aging model Podospora anserina
Aging of biological systems is controlled by various processes which have a potential impact on gene expression. Here we report a genome-wide transcriptome analysis of the fungal aging model Podospora anserina. Total RNA of three individuals of defined age were pooled and analyzed by SuperSAGE (seri...
ORGANISM(S): Podospora anserina 
2013-12-20 | E-MTAB-2016 | biostudies-arrayexpress
MetabolomicsMetaboKit: a comprehensive data extraction tool for untargeted metabolomics (Mouse liver assays)

We have developed MetaboKit, a comprehensive software package for compound identification and relative quantification in mass spectrometry-based untargeted metabolomics analysis. In data dependent acquisition (DDA) analysis, MetaboKit constructs a customized spectral library with compound identit...

2021-11-02 | MTBLS1266 | MetaboLights
ProteomicsIntegrative proteomic and transcriptomic profiling identifies unique and shared functions of oncogenic KRAS and RIT1
Lo A, Holmes K, Mundt F, Moorthi S, Fung I, Fereshetian S, Watson J, Carr SA, Mertins P, Berger A. Aberrant activation of RAS oncogenes is a prevalent event in lung adenocarcinoma, with somatic mutation of KRAS occurring in ~30% of tumors. Recently, we identified somatic mutation of the RAS-family G...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-04-03 | MSV000085225 | MassIVE
TranscriptomicsExpression data of caerulein-treated wild-type mice and KrasG12D-mutated mice at different stages of pancreatic regeneration after inflammatory injury
Consecutive caerulein injections induce an acute pancreatitis in mice. Here, we recorded gene expression levels at different stages of pancreatic regeneration in wild-type mice as well as KrasG12D-mutated mice. Tissue was collected from mice pancreata, cell sorting was not performed. t=0h refers to...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-65146 | biostudies-arrayexpress
TranscriptomicsComparison of histone deacetylase 9-1 mutant (SALK_001723) dry seed transcriptome with Col wild-type
Analysis of the transcriptome of dry hda9-1 mutant seeds with those of Col wild-type seeds, using Affymetrix GeneChip Arabidopsis ATH1 Genome Array. The hda9-1 mutant has reduced primary seed dormancy. We used microarrays to dissect which genes are differentially expressed in the hda9-1 mutant to st...
ORGANISM(S): Arabidopsis thaliana 
2014-09-21 | E-GEOD-50786 | biostudies-arrayexpress
UnknownPartial external biliary diversion in bile salt export pump deficiency: Association between outcome and mutation.
Not available
S-EPMC5550778 | biostudies-literature
UnknownComparative Analysis of Bile-Salt Degradation in Sphingobium sp. Strain Chol11 and Pseudomonas stutzeri Strain Chol1 Reveals Functional Diversity of Proteobacterial Steroid Degradation Enzymes and Suggests a Novel Pathway for Side Chain Degradation.
Not available
S-EPMC8552905 | biostudies-literature
MetabolomicsGNPS JGI Genome Portal Zerbe-Murphy 2017 maize secondary metabolites ( Project ID: 1188675 ) - GNPS
Elucidating the function of the maize (Zea mays) diterpene secondary metabolic network on fitness-promoting plant-microbiome interactions (Proposal ID: 503533). Downloaded from https://genome.jgi.doe.gov/portal/ZerMuretabolites_FD/ZerMuretabolites_FD.info.html
ORGANISM(S): Zea Mays (ncbitaxon:4577) 
2021-03-30 | MSV000087127 | GNPS
TranscriptomicsOvarian transcriptomics over a complete breeding cycle in wild Largemouth bass (Micropterus salmoides) characterizes pathways underlying oocyte maturation and atresia
Background: Follicular growth and maturation in semi-synchronously spawning fish involve numerous cell signaling cascades and different molecular cascades are activated or inhibited during specific stages of oocyte development. The objectives of the current study were to identify molecular pathways ...
ORGANISM(S): Micropterus salmoides 
2011-12-20 | E-GEOD-32930 | biostudies-arrayexpress
TranscriptomicsGene expression comparison in between mitoNEET transgenic vs wild type subcutaneous adipose tissue
mRNA expression was compared in between wild type and mitoNEET transgenic subcutaneous adipose tissue RNA was isolated from subcutaneous adipose tissue from male FVB mice in the light phase. mRNA expression was compared in between wild type and mitoNEET transgenic subcutaneous adipose tissue.
ORGANISM(S): Mus musculus 
2012-07-11 | E-GEOD-39251 | biostudies-arrayexpress
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