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ProteomicsReduced protein expression in a virus attenuated by codon deoptimization
A general means of viral attenuation involves the extensive recoding of synonymous codons in the viral genome. The mechanistic underpinnings of this approach remain unclear, however. Using quantitative proteomics and RNA sequencing, we explore the molecular basis of attenuation in a strain of bacte...
ORGANISM(S): Enterobacteria phage T7 Escherichia coli (strain K12) 
2018-10-24 | PXD006502 | Pride
Codon deoptimization Codon usage Viral attenuation 
ProteomicsAG3C glucose starvation time course
This data set consists of a long term glucose starvation time course of E. coli grown in minimal media for up to two weeks. Unlike previous studies of long term starvation,Our study focuses on the physiological response of E. Coli in stationary phase as a result of being starved for glucose, not on ...
ORGANISM(S): Escherichia coli 
2015-08-24 | PXD002140 | Pride
Bacterial physiology Long term glucose starvation Multi-omic dataset 
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