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ProteomicsSHMT2 controls Burkitt lymphoma cell survival by maintaining an oncogenic TCF3 transcriptional program
In this study, the human Burkitt’s Lymphoma cell line BL60 has been analysed via proteomic and phosphoproteomic analysis for effect of a knock down of the serine hydroxymethyltransferase 2 (shSHMT2) compared to a control construct (shGL2). Concerning the phosphoproteome, these results have been comp...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD018961 | Pride
B cell receptor One carbon metabolism Burkitt’s lymphoma 
Genomicsena-DATASET-UMCU-14-09-2017-12:12:35:225-409 - samples
Whole genome sequencing data for primary tumors, matching control material from blood and their corresponding organoid. Whole transcriptome data for organoids.
EGAD00001003751 | EGA
GenomicsA living biobank of breast cancer organoids captures disease heterogeneity
Breast Cancer (BC) comprises multiple distinct subtypes that differ genetically, pathologically, and clinically. Xeno-transplantation and direct culturing of tumor tissue are increasingly used in drug development and personalized medicine strategies. Here, we describe a robust protocol for long-term...
EGAS00001002158 | EGA
UnknownThe IGNITE Pharmacogenetics Working Group: An Opportunity for Building Evidence with Pharmacogenetic Implementation in a Real-World Setting.
Not available
S-EPMC5421730 | biostudies-literature
UnknownMACF1 Mutations Encoding Highly Conserved Zinc-Binding Residues of the GAR Domain Cause Defects in Neuronal Migration and Axon Guidance.
Not available
S-EPMC6288423 | biostudies-literature
UnknownMultisite Investigation of Outcomes With Implementation of CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention.
Not available
S-EPMC5775044 | biostudies-literature
UnknownSurgical and Blood-Based Minimal Residual Disease in Patients with Ovarian Cancer after First-line Therapy: Clinical Outcomes and Translational Opportunities.
Not available
S-EPMC12485385 | biostudies-literature
UnknownDrosophila functional screening of de novo variants in autism uncovers damaging variants and facilitates discovery of rare neurodevelopmental diseases.
Not available
S-EPMC8983390 | biostudies-literature
UnknownNovel experimental setup for megahertz X-ray diffraction in a diamond anvil cell at the High Energy Density (HED) instrument of the European X-ray Free-Electron Laser (EuXFEL).
Not available
S-EPMC8127375 | biostudies-literature
UnknownMechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice.
Not available
S-EPMC10005179 | biostudies-literature
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