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TranscriptomicsComprehensive characterization and RNA-Seq profiling of the HD-Zip transcription factor family in soybean (Glycine max) during dehydration and salt stress
Background The homeodomain leucine zipper (HD-Zip) transcription factor family is one of the largest plant specific superfamilies, and includes genes with roles in modulation of plant growth and response to environmental stresses. Many HD-Zip genes are characterized in Arabidopsis (Arabidopsis thal...
ORGANISM(S): Glycine max 
2014-11-01 | E-GEOD-57252 | biostudies-arrayexpress
TranscriptomicsAdult mouse liver following benzo(a)pyrene (BaP) treatment: miRNA and mRNa profiling
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2010-10-18 | E-GEOD-18841 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse lung tissue after exposure to mainstream tobacco smoke
We have examined the impact of subchronic levels of tobacoo smoke on murine lungs. We have used high density DNA microarray and analysed lung tissues from mice exposed to mainstream tobacco smoke (MTS). Our results reveal induction of inflammatory cytokine interleukin-6 (IL-6) and its antagonist sup...
ORGANISM(S): Mus musculus 
2009-09-18 | E-GEOD-12930 | biostudies-arrayexpress
TranscriptomicsRecurrent 15q13 microdeletions
We report a recurrent microdeletion syndrome causing mental retardation, epilepsy and variable facial and digital dysmorphisms. We describe nine patients, including six probands; two with de novo deletions, two who inherited the deletion from an affected parent, and two with unknown inheritance. The...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10189 | biostudies-arrayexpress
TranscriptomicsSub-chronic forestomach transcriptional response in adult male MutaTMMouse following oral exposure to benzo(a)pyrene
Benzo(a)pyrene is a well-established human carcinogen in humans and rodents. In the present study, we sought to determine the dose- and time-dependent changes in gene expression upon oral exposure to benzo(a)pyrene. Adult male MutaTMMouse were exposed to three doses of benzo(a)pyrene or vehicle cont...
ORGANISM(S): Mus musculus 
2013-09-27 | E-GEOD-43438 | biostudies-arrayexpress
TranscriptomicsPulmonary gene and microRNA expression changes in mice exposed to benzo(a)pyrene by oral gavage
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed, carcinogenic environmental contaminants produced as a consequence of the incomplete combustion of fossil fuels. Benzo[a]pyrene (BaP) is a very extensively studied prototypical PAH. We recently reported a complete lack of change in micro...
ORGANISM(S): Mus musculus 
2011-10-03 | E-GEOD-24751 | biostudies-arrayexpress
TranscriptomicsPulmonary gene expression in MutaTMMouse orally gavaged with three doses of benzo(a)pyrene and vehicle control
In this study, we investigate mRNA profiles in lung of mice exposed to benzo(a)pyrene. Male mice were exposed to three doses (25, 50, and 75 mg/kg/day BaP) for 28 days and profiles were examined three days post-exposure. Our analyses reveal that BaP causes pulmonary specific cellular transformation ...
ORGANISM(S): Mus musculus 
2012-10-03 | E-GEOD-35718 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Apoe knockouts treated with SRM2975 and C57Bl/6 mice treated with exhaust particles reveals Serum amyloid and serum amyloid P are not induced in response to diesel exhaust particles or carbon black
W evaluated an experimental particle exposure model, including markers of the acute phase system assessed as the hepatic mRNA expression of Sap, the murine homologue of CRP, and Saa1 and Saa3. Experiment Overall Design: 12-13 weeks old Apoe knockout mice (C57BL/6-Apoe tm1) mice were injected intrape...
ORGANISM(S): Mus musculus 
2009-05-02 | E-GEOD-11346 | biostudies-arrayexpress
MetabolomicsGut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives.

BACKGROUND & AIMS: The cause of Crohn's disease (CD) is unknown, but the current hypothesis is that microbial or environmental factors induce gut inflammation in genetically susceptible individuals, leading to chronic intestinal inflammation. Case-control studies of patients...

2023-11-16 | MTBLS300 | MetaboLights
ProteomicsHX mapping of the binding interface between a DCP and murine LRRC-15
This dataset is associated with the manuscript titled: Development and Structural Characterization of LRRC15-binding Disulfide-Constrained Peptides for Enhanced Tumor Imaging Authors: Benjamin J. Tombling, Fei Cai, Tim Wendorff, Annie Ogasawara, Herman S. Gill, Jeff N. Tinianow, Andrew Chang, Aaron ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2026-02-20 | MSV000100920 | MassIVE
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