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TranscriptomicsMicroprocessor mediates transcription termination in long noncoding microRNA genes
MicroRNA (miRNA) play a major role in the post-transcriptional regulation of gene expression. In mammals most miRNA derive from the introns of protein coding genes where they exist as hairpin structures in the primary gene transcript, synthesized by RNA polymerase II (Pol II). These are cleaved co-t...
ORGANISM(S): Homo sapiens 
2015-03-02 | E-GEOD-58838 | biostudies-arrayexpress
UnknownValidation of the Critical-Care Pain Observation Tool-Neuro in brain-injured adults in the intensive care unit: a prospective cohort study.
Not available
S-EPMC8042624 | biostudies-literature
MetabolomicsGNPS Burkholderia thailandensis and Bacillus spp. Monocultures and B. thailandensis + Bacillus velezensis co-cultures
Extraction samples of Bacillus spp. and B. thailandensis in mono and co-culture. Extracts were analyzed with LC-MS/MS to identify compounds detected within the aforementioned samples. Included are extracts of B. thailandensis monocultures, several Bacillus spp. monocultures, and co-cultures of B. t...
ORGANISM(S): Bacillus Subtilis (ncbitaxon:1423) Paenibacillus Lactis (ncbitaxon:228574) Bacillus Nealsonii (ncbitaxon:115979) Virgibacillus Pantothenticus (ncbitaxon:1473) Burkholderia Thailandensis E264 (ncbitaxon:271848) Bacillus Clausii (ncbitaxon:79880) Bacillus Velezensis (ncbitaxon:492670) Bacillus Licheniformis (ncbitaxon:1402) Bacillus Simplex (ncbitaxon:1478) Bacillus Megaterium (ncbitaxon:1404) Brevibacillus Borstelensis (ncbitaxon:45462) 
2022-12-27 | MSV000090970 | GNPS
TranscriptomicsMRE11 Deficiency Increases Sensitivity to Poly(ADP-ribose) Polymerase Inhibition in Microsatellite Unstable Colorectal Cancers.
We have performed bioinformatic approaches to identify the level of enrichment between gene expression profiles characterizing MSI tumors and gene changes induced in vitro by the PARP-1 inhibitor Phenanthridinone and others using the Connectivity Map tool. In a first step, we have anyzed the express...
ORGANISM(S): Homo sapiens 
2011-04-07 | E-GEOD-26682 | biostudies-arrayexpress
UnknownIncreased Antifungal Drug Resistance in Clinical Isolates of Cryptococcus neoformans in Uganda.
Not available
S-EPMC4649209 | biostudies-literature
TranscriptomicsIGR_Michels_PARP
Non-small cell lung cancer (NSCLC) is often treated with cisplatin (CDDP). Here, we report that two distinct poly(ADP-ribose) polymerase (PARP) inhibitors exhibited a hyperadditive combination effect with CDDP to kill NSCLC cells. A majority of CDDP-resistant cell lines and clones exhibited constitu...
ORGANISM(S): Homo sapiens 
2013-10-31 | E-MTAB-1353 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human xenografted nasopharyngeal carcinoma tumor cell lines and an untransformed diploid fibroblast cell line
The aim of this experiment was to investigate the gene expression profile of two xenografted nasopharyngeal carcinoma tumors - C15 and C17 – which are international reference tools for biological investigations of this type of disease. C15 and C17 transcriptome was profiled by comparison with human...
ORGANISM(S): Homo sapiens 
2007-12-01 | E-TABM-382 | biostudies-arrayexpress
UnknownAssociation of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19.
Not available
S-EPMC10219675 | biostudies-literature
UnknownThrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry.
Not available
S-EPMC10439444 | biostudies-literature
UnknownAnemia Acuity Effect on Transfusion Strategies in Acute Myocardial Infarction: A Secondary Analysis of the MINT Trial.
Not available
S-EPMC11530937 | biostudies-literature
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