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TranscriptomicsC2C12 murine myoblast cell line and 48 h 10 uM BIO treated C2C12 cellulate
In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BIO) to attempt to reproduce this behavior in mammalian muscle culture. C2C12 myotubes derived from th...
ORGANISM(S): Mus musculus 
2011-12-08 | E-GEOD-34238 | biostudies-arrayexpress
Transcriptomicskdrl:eGFP+ ECs isolated from wildtype, etsrp-null, npas4l-null, and sox32-null zebrafish embryos
Microarray analysis of triplicate RNA samples isolated from kdrl:eGFP-sorted ECs of wildtype, npas4l-/-, etsrp-/-, and sox32-/- zebrafish embryos in Tg(kdrl:EGFP) transgenic background between 18 and 18.5 hpf.
ORGANISM(S): Danio rerio 
2020-10-20 | E-MTAB-9698 | biostudies-arrayexpress
TranscriptomicsRNA-seq of whole blood samples from healthy adults randomized to receive either placebo or metformin followed by live-attenuated YF-17D vaccination
RNAseq was carried out to identify the transcriptomic changes that occur in healthy adult volunteers given either placebo or metformin from 3-days before to 3-days after live-attenuated YF-17D vaccination. Whole blood was collected at baseline (before placebo/metformin therapy), before YF-17D vaccin...
ORGANISM(S): Homo sapiens 
2025-01-01 | E-MTAB-13265 | biostudies-arrayexpress
UnknownClinical utility of random anti-tumor necrosis factor drug-level testing and measurement of antidrug antibodies on the long-term treatment response in rheumatoid arthritis.
Not available
S-EPMC4843946 | biostudies-literature
TranscriptomicsHistone deacetylase inhibition replicates aspects of the adaptive response to exercise and improves muscle metabolism and cardiac function in obesity.
Drugs used to treat obesity and type 2 diabetes have limited efficacy in directly normalising muscle metabolism. The discovery of molecules mediating exercise adaptations, and drugs that modulate their activity, is a potential strategy to address this therapeutic gap. Here we show that genetic impai...
ORGANISM(S): Mus musculus 
2015-01-28 | E-GEOD-54642 | biostudies-arrayexpress
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