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TranscriptomicsImplications of high level pseudogene transcription in Mycobacterium leprae
Approximately half of M. lepraeâ??s transcriptome consists of inactive gene products. This has an impact on overall energy and resource consumption without potential benefit to this organism. However, multiple translational â??silencingâ?? mechanisms are present, reducing additional energy and resou...
ORGANISM(S): Mycobacterium leprae 
2010-06-24 | E-GEOD-17191 | biostudies-arrayexpress
UnknownVariable active site loop conformations accommodate the binding of macrocyclic largazole analogues to HDAC8.
Not available
S-EPMC4382410 | biostudies-literature
UnknownOnion-like glycodendrimersomes from sequence-defined Janus glycodendrimers and influence of architecture on reactivity to a lectin.
Not available
S-EPMC4747702 | biostudies-literature
UnknownMaternal undernutrition during periconceptional period affects whole-genome ovine muscle methylation in adult offspring.
Not available
S-EPMC9387600 | biostudies-literature
UnknownProtocol for establishing primary human lung organoid-derived air-liquid interface cultures from cryopreserved human lung tissue.
Not available
S-EPMC10696416 | biostudies-literature
TranscriptomicsComparison of Normal Prostate Fibroblasts Overexpressing Cyclin D1 and Carcinoma Associated Fibroblasts
The cyclin D1 oncogene encodes the regulatory subunit of a holoenzyme that phosphorylates and inactivates the Rb protein and promotes progression through G1 to S phase of the cell cycle. Several prostate cancer cell lines and a subset of primary prostate cancer samples have increased cyclin D1 prote...
ORGANISM(S): Homo sapiens 
2007-08-31 | E-GEOD-6936 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression of cancer and matched adjacent tissues from 7 testicular germ cell tumors and 10 transitional cell carcinomas of bladder
Genome-wide gene expression profile using deep sequencing technologies can drive the discovery of cancer biomarkers and therapeutic targets. Such efforts are often limited to profiling the expression signature of either mRNA or microRNA (miRNA) in a single type of cancer.Here we provided an integrat...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-31616 | biostudies-arrayexpress
TranscriptomicsFunctional analysis of transcriptome dynamics during growth in Angus cattle longissimus muscle
The bovine transcriptome dynamics in logissimus muscle (LM) during the post-natal growth remain unknown. Biopsies of LM from Angus steers were harvested at 0, 60, 120, and 220 d from early-weaning. A 13,153 bovine oligonucleotide array was used for transcript profiling. Functional analysis of microa...
ORGANISM(S): Bos taurus 
2013-06-21 | E-GEOD-48136 | biostudies-arrayexpress
UnknownWhy Do Membranes of Some Unhealthy Cells Adopt a Cubic Architecture?
Not available
S-EPMC5200934 | biostudies-literature
ProteomicsAn Automated High-throughput Affinity Capture-Mass Spectrometry Platform with Data-Independent Acquisition
Affinity capture (AC) combined with mass spectrometry (MS)-based proteomics is highly utilized throughout the drug discovery pipeline to determine small molecule target selectivity and engagement. However, the tedious sample preparation steps and time-consuming MS acquisition process has limited its...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-08-12 | MSV000095587 | MassIVE
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