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Chromatin immunoprecipitation experiment to identify H-NS and RNA polymerase (beta-subunit) binding sites on the Salmonella Typhimurium chromosome
ORGANISM(S): Salmonella typhimurium 
The Sfh protein is encoded by self-transmissible plasmids involved in human typhoid and is closely related to the global regulator H-NS. We have found that Sfh provides a stealth function that allows the plasmids to be transmitted to new bacterial hosts with minimal effects on their fitness. Introdu...
ORGANISM(S): Salmonella enterica serotype Typhimurium 
BxPc-3, Miapaca-2 and ASPC-1 cell lines were treated with 100 µM NS-398 in DMSO or with DMSO alone (control) for 48 h. Total-RNA from each sample was isolated with the RNeasy kit of Qiagen (Hilden, Germany) according to the manufacturer's protocol. The integrity of the isolated RNA was checked on an...
ORGANISM(S): Homo sapiens 
Minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) are patterns of kidney injury observed in the filtering units of the kidney known as glomeruli. From the NURTuRE cohort of individuals with nephrotic syndrome (NS), we performed laser microdissection and mass spectrometry ana...
ORGANISM(S): Homo sapiens (Human) 
2024-07-15 | PXD053362 | Pride
Cholera is a diarrheal disease caused by Vibrio cholerae of serogroups O1 and O139 that affects impoverished populations worldwide. The histone-like nucleoid structuring protein (H-NS) is a global regulator of environmentally-regulated gene expression that plays a fundamental role in V. cholerae ada...
ORGANISM(S): Vibrio cholerae 
We looked at H-NS bound sites in wild type Yersinia pestis and in a mutant strain in which the psaE gene was deleted.
ORGANISM(S): Yersinia pestis 
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