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GenomicsGenome-wide Analysis of Transcriptional Regulators in Human Blood Stem/Progenitor Cells reveals a densely interconnected network of coding and non-coding genes.
Combinatorial transcription factor (TF) interactions regulate hematopoietic stem cell formation, maintenance and differentiation, and are increasingly recognised as drivers of stem cell signatures in cancer. However, genome-wide combinatorial binding patterns for key regulators do not exist in prim...
ORGANISM(S): Homo sapiens 
2013-09-03 | E-GEOD-45144 | biostudies-arrayexpress
UnknownOligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains.
Not available
S-EPMC6204946 | biostudies-literature
UnknownGenetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource.
Not available
S-EPMC5204341 | biostudies-literature
UnknownFrequency and signature of somatic variants in 1461 human brain exomes.
Not available
S-EPMC6544539 | biostudies-literature
UnknownMitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains.
Not available
S-EPMC5290662 | biostudies-literature
ProteomicsDemo datasets for AutoCCS: Automated collision cross section calculation software for ion mobility spectrometry-mass spectrometry
Agilent Tunemix samples analyzed on three IMS-MS platforms with nitrogen gas: 1) stepped-field drift tube IMS-MS, 2) single-field drift tube IMS-MS, and 3) SLIM-based IMS-MS. Also, tetraalkylammonium (TAA) salt samples analyzed with SLIM-based IMS-MS using helium gas.
ORGANISM(S): Unclassified Sequences (ncbitaxon:12908) 
2020-08-19 | MSV000085979 | MassIVE
UnknownEvolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers.
Not available
S-EPMC5709185 | biostudies-literature
GenomicsEstrogen Receptor Positive Breast Cancer: Aromatase Inhibitor Response Study

Highly variable outcomes are observed in patients with estrogen receptor positive (ER+) breast cancer who undergo preoperative estrogen deprivation therapy with aromatase inhibitors (AI). In this study, 46 tumor and normal genomes and 31 exomes of participants selected from two clinical trials of...

phs000472.v1.p1 | EGA
UnknownPlant-symbiotic fungi as chemical engineers: multi-genome analysis of the clavicipitaceae reveals dynamics of alkaloid loci.
Not available
S-EPMC3585121 | biostudies-literature
GenomicsWhole Genome Sequencing of a Triple Negative Breast Cancer Patient: Matched Primary Tumor, Normal, Metastasis and Xenograft samples

Breast Cancer Subject Participant ID 700064 (Source Sample names: 6888 and 206). We used massively parallel DNA sequencing technologies to screen entire genomes, in an unbiased manner, for genetic changes associated with tumor growth and metastasis. We describe the complete genome sequence ...

phs000245.v1.p1 | EGA
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