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MetabolomicsBiochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles (NMR assay)
Parkinson’s disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central to the pathogenesis. Currently, treatments that slow dise...
2019-02-07 | MTBLS640 | MetaboLights
MetabolomicsMetabolic Profiling of CSF from People Suffering from Sporadic and LRRK2 Parkinson's Disease: A Pilot Study
CSF from unique groups of Parkinson's disease (PD) patients was biochemically profiled to identify previously unreported metabolic pathways linked to PD pathogenesis, and novel biochemical biomarkers of the disease were characterized. Utilizing both 1H NMR and DI-LC-MS/MS we quantitatively profiled ...
2022-09-02 | MTBLS863 | MetaboLights
UnknownX-ray inactivation of RNA viruses without loss of biological characteristics.
Not available
S-EPMC7722841 | biostudies-literature
UnknownDetermination of Thiol Protonation States by Sulfur X-ray Spectroscopy in Biological Systems.
Not available
S-EPMC11892467 | biostudies-literature
UnknownIdentification of a vimentin-expressing α-cell phenotype in CF and normal pancreas.
Not available
S-EPMC11850051 | biostudies-literature
TranscriptomicsNF-κB target gene microarray in HAECs in response to Pseudomonas aeruginosa
An NF-κB target gene array (Panomics, Inc., Redwood City, CA) was performed to profile the PAO1-dependent expression pattern of 111 NF-kB-regulated genes in primary human airway epithelial cells (HAECs). A small scale microarray was carried out using NF-κB target gene array kit (Panomics, Inc., Redw...
ORGANISM(S): Homo sapiens 
2007-09-08 | E-GEOD-8986 | biostudies-arrayexpress
UnknownTemporal characteristics of gamma rhythm constrain properties of noise in an inhibition-stabilized network model.
Not available
S-EPMC10502791 | biostudies-literature
UnknownHarnessing interpretable and unsupervised machine learning to address big data from modern X-ray diffraction.
Not available
S-EPMC9214512 | biostudies-literature
UnknownShape analysis of gamma rhythm supports a superlinear inhibitory regime in an inhibition-stabilized network.
Not available
S-EPMC8880865 | biostudies-literature
TranscriptomicsINTRA_specific hybs: A Burst of Segmental Duplications in the African Great Ape Ancestor
Wilson and King were among the first to recognize that the extent of phenotypic change between humans and great apes was dissonant with the rate of molecular change. Proteins are virtually identical; cytogenetically there are few rearrangements that distinguish ape-human chromosomes; rates of single...
ORGANISM(S): Pan troglodytes 
2010-05-22 | E-GEOD-13885 | biostudies-arrayexpress
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