Wiltzsch Vivien V - OmicsDI

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Proteomics (2)

Organisms

Bordetella pertussis B1917 (2)
Phytophthora palmivora (2)
Spinacia sp. (2)
Spraguea lophii 42_110 (2)
Rhodococcus qingshengii JCM 15477 (2)
Rhizobium johnstonii 3841 (2)
Naja nigricincta nigricincta (2)
Ferrimicrobium acidiphilum DSM 19497 (2)
Helicoverpa armigera armigera (2)
Corynebacterium ulcerans bv. belfanti (2)
Spodoptera exigua (2)
Spodoptera littoralis (2)
Burkholderia dolosa AU0158 (2)
Salmonella enterica subsp. enterica serovar Enteritidis str. EC20120200 (2)
Hydrogenophaga pseudoflava (2)
Pseudomonas amygdali pv. tabaci str. ATCC 11528 (2)
Ectopseudomonas oleovorans (2)
Escherichia coli M1 (2)
Bifidobacterium pseudolongum subsp. globosum DSM 20092 (2)
Rhodococcus sp. DN22 (2)
Phocaeicola dorei CL02T00C15 (2)
Aspergillus flavus FRR 342 (2)
Nitrospira moscoviensis (2)
Sorex araneus (2)
Anneissia japonica (2)
Crocuta (2)
Escherichia coli ETEC H10407 (2)
Eggerthella phage P3 (2)
Clostridium botulinum A str. Hall (2)
Cylindrospermopsis raciborskii CS-506 (2)

Repository

pride (2)

Tissue

Long bone (1)
Femur (1)
Bone (1)

Disease

Type 2 diabetes mellitus (1)
Wounds and Injuries (1)

Technology Type

Bottom-up proteomics (2)
Mass Spectrometry (2)
DiaPASEF (1)
Data-independent acquisition (1)

Publication Date

2026 (1)
2025 (1)

Lab affiliation

1) Department Preclinical Development and Validation, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany; 2) Institute for Bioanalysis, University of Applied Science Coburg, Coburg, Germany (2)

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Proteomic profiling of scaffold-guided bone healing in type 2 diabetes rat model with critical-sized bone defect

Type 2 diabetes mellitus significantly impairs bone healing, with delayed regeneration observed in over 60% of diabetic patients. This study investigated the molecular mechanisms underlying diabetes-associated compromised regeneration using time-resolved proteome profiling of critical-sized femoral ...

ORGANISM(S): Rattus norvegicus (Rat)

2026-04-16 | PXD071312 | Pride

A Novel Two-Step Proteome Extraction Protocol for Bone Tissue: Enhancing Low-Abundance Protein Detection and Multi-Omics Compatibility

Bone metabolism is a dynamic process involving osteoblasts, osteoclasts, and osteocytes, which maintain skeletal integrity through continuous remodelling. Disruptions in this homeostasis – caused by mineral or hormonal imbalances, systemic metabolic or inflammatory conditions, or genetic predisposit...

ORGANISM(S): Rattus norvegicus (Rat)

2025-08-13 | PXD056459 | Pride

Proteome extraction Rat Bone tissue Multi-omics Comparison

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