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TranscriptomicsExpression data from pulmonary metastases of clear-cell renal cell carcinoma
The understanding of metastatic spread is limited and molecular mechanisms causing particular characteristics of metastasis, like varying dormancy periods of Mets originating from the same primary tumor entity or the differing number of Mets in patients with the same primary tumor, are largely unkno...
ORGANISM(S): Homo sapiens 
2009-01-13 | E-GEOD-14378 | biostudies-arrayexpress
TranscriptomicsExpression data from primary Glioblastoma in adults
Gene expression profiling revealed over-representation of a distinct (proneural-like) expression signature in long-term survivors that was linked to IDH1/2 mutation. However, among the IDH1/2-wildtype patients, tumors from long-term survivors did not show distinct gene expression profiles and includ...
ORGANISM(S): Homo sapiens 
2014-03-27 | E-GEOD-53733 | biostudies-arrayexpress
TranscriptomicsGM-CSF induced gene-regulation in human monocytes
Human and murine studies showed that granulocyte macrophage colony-stimulating factor (GM-CSF) exerts beneficial effects in intestinal inflammation. To explore whether GM-CSF mediates its effects via monocytes, we analyzed effects of GM-CSF on monocytes in vitro and assessed the immunomodulatory pot...
ORGANISM(S): Homo sapiens 
2014-11-27 | E-GEOD-63662 | biostudies-arrayexpress
UnknownResistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia.
Not available
S-EPMC12805919 | biostudies-literature
TranscriptomicsExpression data from pulmonary metastases and primary tumors of clear-cell renal cell carcinoma (ccRCC) with different disease-free survivals
The understanding of metastatic spread is limited and molecular mechanisms causing particular characteristics of metastasis are largely unknown. This comprises the extremely varying dormancy periods of tumor cells in the secondary organ after metastatic spread, represented by the disease-free surviv...
ORGANISM(S): Homo sapiens 
2010-07-30 | E-GEOD-22541 | biostudies-arrayexpress
TranscriptomicsSuppression of NCALD protects against spinal muscular atrophy by restoring impaired endocytosis
Spinal muscular atrophy (SMA) is a common genetic motor neuron (MN) disease caused by low levels of the ubiquitously expressed housekeeping survival motor neuron (SMN) protein, whereas concomitant overexpression of plastin 3 (PLS3) protects from SMA. Here we identify neurocalcin delta (NCALD), a neu...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-58316 | biostudies-arrayexpress
TranscriptomicsExpression data from cerebral tumors of WHO grade II and III
Molecular profiling of cerebral gliomas distinguishes biologically distinct tumor groups and provides prognostically relevant information beyond histological classification and IDH1/2 mutation status. We performed microarray-based genome- and transcriptome-wide molecular profiling of primary tumor s...
ORGANISM(S): Homo sapiens 
2015-04-30 | E-GEOD-61374 | biostudies-arrayexpress
UnknownPerformance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia.
Not available
S-EPMC9877422 | biostudies-literature
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