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MetabolomicsMulti‐omics identify xanthine as a pro‐survival metabolite for nematodes with mitochondrial dysfunction
Aberrant mitochondrial function contributes to the pathogenesis of various metabolic and chronic disorders. Inhibition of insulin/IGF-1 signaling (IIS) represents a promising avenue for the treatment of mitochondrial diseases, although many of the molecular mechanisms underlying this beneficial effe...
2019-02-28 | MTBLS794 | MetaboLights
ProteomicsActin-nucleation promoting factor N-WASP influences alpha-synuclein condensates and pathology
Abnormal intraneuronal accumulation of soluble and insoluble alpha-synuclein (alpha-Syn) is one of the main pathological hallmarks of synucleinopathies, such as Parkinson’s disease (PD). It has been well- documented that the reversible liquid-liquid phase separation of alpha-Syn can modulate synapti...
ORGANISM(S): Homo Sapiens (human) Caenorhabditis Elegans 
2025-03-22 | PXD050719 | JPOST Repository
UnknownBCL7A-containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation
Not available
S-SCDT-10_15252-EMBJ_2022110595 | biostudies-other
Unknowncest-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants
Not available
S-SCDT-EMBOR-2021-52606V1 | biostudies-other
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