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TranscriptomicsTranscription profiling of Lotus japonicus grown under different salt acclimation regimes
Model legume Lotus japonicus was subjected to non-lethal long-term salinity and profiled at the transcriptomic level. Three independent experiments were performed, testing two experimental designs: a traditional gradual acclimation following a step-wise increase of salt concentration and an initial ...
ORGANISM(S): Lotus japonicus 
2008-07-17 | E-MEXP-1204 | biostudies-arrayexpress
GenomicsHydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster (MeDIP-Seq)
Differentiation is accompanied by extensive epigenomic reprogramming, leading to the repression of stemness factors and the transcriptional maintenance of activated lineage-specific genes. Here we used the mammalian Hoxa cluster of developmental genes as a model system to follow changes in DNA modif...
ORGANISM(S): Homo sapiens 
2012-05-02 | E-GEOD-33129 | biostudies-arrayexpress
TranscriptomicsINDUCTION OF PANCREATIC ISLET CELL DIFFERENTIATION BY THE NEUROGENIN-NEUROD CASCADE
Neurog3 and NeuroD1 share the ability to induce endocrine differentiation when expressed ectopically in vivo (Apelqvist et al., 1999; Schwitzgebel et al., 2000; Grapin-Botton et al., 2001) and in vitro (Heremans et al., 2002; Gasa et al., 2004), suggesting that they target a common set of genes. To...
ORGANISM(S): Mus musculus 
2007-08-29 | E-GEOD-7884 | biostudies-arrayexpress
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on Arabidopsis thaliana Col-0 (B)
New metabolic profiling technologies provide data on a wider range of metabolites than traditional targeted approaches. Metabolomic technologies currently facilitate acquisition of multivariate metabolic data using diverse, mostly hyphenated, chromatographic detection systems, such as GC-MS or liqui...
2015-09-14 | MTBLS41 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on Arabidopsis thaliana Col-0 (C)
New metabolic profiling technologies provide data on a wider range of metabolites than traditional targeted approaches. Metabolomic technologies currently facilitate acquisition of multivariate metabolic data using diverse, mostly hyphenated, chromatographic detection systems, such as GC-MS or liqui...
2015-09-14 | MTBLS42 | MetaboLights
MetabolomicsMining for metabolic responses to long-term salt stress: a case study on Arabidopsis thaliana Col-0 (A)
New metabolic profiling technologies provide data on a wider range of metabolites than traditional targeted approaches. Metabolomic technologies currently facilitate acquisition of multivariate metabolic data using diverse, mostly hyphenated, chromatographic detection systems, such as GC-MS or liqui...
2015-09-14 | MTBLS22 | MetaboLights
ProteomicsInvestigation of protein allocation and utilization in the versatile chemolithoautotroph Cupriavidus necator
The aim of this study was to understand how autotrophic (CO2-fixing) bacteria balance the different needs for substrate assimilation, growth functions, and resilience in order to thrive in their environment.To this end, the proteome of the model chemolithoautotroph Ralstonia eutropha a.k.a. Cupriavi...
ORGANISM(S): Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha) 
2022-02-17 | PXD024819 | Pride
Cupriavidus necator Shotgun proteomics Resource balance Msgf+ Cellular economy Openms Substrate limitation Ralstonia eutropha Resource allocation Data-dependent acquisition 
UnknownOn the emergence of P-Loop NTPase and Rossmann enzymes from a Beta-Alpha-Beta ancestral fragment.
Not available
S-EPMC7758060 | biostudies-literature
UnknownComprehensive subtyping of Parkinson's disease patients with similarity fusion: a case study with BioFIND data.
Not available
S-EPMC8448859 | biostudies-literature
TranscriptomicsGene expression data of cSHMT mutant, heterozygous, and wild-type mouse colons
Folate-mediated one-carbon metabolism is required for purine, thymidylate, and S-adenosylmethionine synthesis. Impairments in folate metabolism diminish cellular methylation potential and genome stability. Cytoplasmic serine hydroxymethyl transferase (cSHMT) regulates partitioning between thymidylat...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-14645 | biostudies-arrayexpress
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