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ProteomicsA genetic model for in vivo proximity labeling of the mammalian secretome
Yang R, Meyer AS, Droujinine I, Udeshi ND, Hu Y, Guo J, McMahon J, Carey DK, Xu C, Qiao F, Sha J, Qin S, Rocco D, Wohlschlegel J, Ting AY, Carr SA, Perrimon N, McMahon AP. 2022. Organ functions are highly specialized and interdependent. Tissue-specific secreted factors play a critical role in organ...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-16 | MSV000088848 | MassIVE
ProteomicsHigh-field asymmetric waveform ion mobility spectrometry interface enhances parallel reaction monitoring on an Orbitrap mass spectrometer
High-field asymmetric waveform ion mobility spectrometry (FAIMS) enables gas phase separations on a chromatographic timescale and has become a useful tool for proteomic applications. Despite its emerg-ing utility, however, the molecular determinants underlying peptide separation by FAIMS have not be...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-07 | MSV000089014 | MassIVE
ProteomicsCMMB-based isopropanol gradient peptide fractionation (CIF) enables rapid and robust off-line peptide mixture fractionation in bottom-up proteomics
HEK293 cells lysates fractionated by various different methods
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-22 | MSV000085458 | MassIVE
ProteomicsBottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu
LC-MS/MS analysis of fractionated extracts from Plasmodium falciparum
ORGANISM(S): Plasmodium Falciparum (ncbitaxon:5833) 
2019-06-16 | MSV000083980 | MassIVE
TranscriptomicsProcessing of Drosophila endo-siRNAs depends on a specific Loquacious isoform
Drosophila melanogaster expresses three classes of small RNAs, which are classified according to their mechanisms of biogenesis. MicroRNAs are ~22-23-nt, ubiquitously expressed small RNAs that are sequentially processed from hairpin-like precursors by Drosha/Pasha and Dcr-1/Loquacious complexes. Mic...
ORGANISM(S): Drosophila melanogaster 
2009-07-30 | E-GEOD-17171 | biostudies-arrayexpress
ProteomicsDynamic Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery Requires Iron-Sulfur Cluster Incorporation of CIAO3
Cytosolic iron-sulfur (Fe-S) cluster assembly (CIA) pathway delivers Fe-S clusters to nuclear and cytosolic Fe-S proteins involved in essential cellular functions. This delivery process is regulated by availability of iron and oxygen, but it remains unclear how CIA components orchestrate the cluster...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-16 | MSV000088394 | MassIVE
TranscriptomicsProteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members
In germ cells, Piwi proteins interact with a specific class of small non-coding RNAs, piwi-interacting RNAs (piRNAs). Together, these form a pathway that represses transposable elements, thus safeguarding germ cell genomes. While basic models describe the operation of piRNA pathways, neither the pr...
ORGANISM(S): Mus musculus 
2009-07-25 | E-GEOD-17319 | biostudies-arrayexpress
ProteomicsTMT analysis of flagellum skeletons from MIP knockdown parasites
TMT data associated with Shimogawa et al. 'FAP106 is an interaction hub required for stable assembly of conserved and lineage-specific proteins at the cilium inner junction'
ORGANISM(S): Trypanosoma Brucei (ncbitaxon:5691) 
2022-11-07 | MSV000090661 | MassIVE
ProteomicsAPEX2 proximity proteomics of microtubule inner proteins FAP45 and FAP52
APEX2-based proximity proteomics data associated with Shimogawa et al. 'FAP106 is an interaction hub required for stable assembly of conserved and lineage-specific proteins at the cilium inner junction'
ORGANISM(S): Trypanosoma Brucei (ncbitaxon:5691) 
2022-11-07 | MSV000090660 | MassIVE
ProteomicsIron-Regulated Assembly of the Cytosolic Iron-Sulfur Cluster Biogenesis Machinery
The cytosolic iron-sulfur (Fe-S) cluster assembly (CIA) pathway delivers Fe-S clusters to nuclear and cytosolic Fe-S proteins involved in essential cellular functions. Although the delivery process is regulated by the availability of iron and oxygen, it remains unclear how CIA components orchestrate...
ORGANISM(S): Homo Sapiens 
2022-06-06 | PXD033557 | panorama
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