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ProteomicsProteomic and metabolomic signatures of rectal tumor discriminate patients with different responses to preoperative radiotherapy
Background: Neoadjuvant radiotherapy (neo-RT) is widely used in locally advanced rectal cancer (LARC) as a component of radical treatment. Despite the advantages of neo-RT, which typically improves outcomes in LARC patients, the lack of reliable biomarkers that predict response and monitor the effic...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD048647 | Pride
Tissue Proteomics Metabolomics Rectal cancer Radiotherapy 
ProteomicsBiopsy proteome-based classification of T-cell-mediated kidney allograft rejection
T cell-mediated rejection (TCMR) remains a challenge in kidney transplantation. Based on a histopathological biopsy examination, patients can be classified into groups defining their kidney’s status, i.e. no rejection (NR), borderline rejection (BR) and acute rejection (AR). Yet, this classification...
ORGANISM(S): Homo sapiens (Human) 
2025-10-27 | PXD064523 | Pride
Borderline rejection Kidney transplant rejection Immunohistochemical staining T-cell mediated rejection Mass spectrometry proteomics 
MetabolomicsMetabolomic Aspects of Conservative and Resistance-related Elements of Response to Fusarium culmorum in the Grass Family

BACKGROUND: Fusarium head blight (FHB) is a serious fungal disease of crop plants due to substantial yield reduction and production of mycotoxins in the infected grains. The breeding progress in increasing resistance with maintaining a high yield is not possible without a thoroug...

2022-10-27 | MTBLS1748 | MetaboLights
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