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TranscriptomicsTranscrioptome analysis of human primary macrophages stimulated by bacterial endotoxin lipopolysaccharide (LPS), and (1,3)-b-glucans, curdlan and glucan from bakerM-BM-4s yeast (GBY)
We performed gene expression microarray experiments to compare the global transcriptional response induced by b-glucans and LPS with their secretomes. We identified 1683, 767 and 1447 genes with over two-fold increase or decrease in LPS-, curdlan- or GBY-stimulated macrophages, respectively. We show...
ORGANISM(S): Homo sapiens 
2014-05-15 | E-GEOD-32282 | biostudies-arrayexpress
TranscriptomicsInhalation of rod-like carbon nanotubes causes unconventional asthma
Exposure to rod-shaped carbon nanotubes reveals novel innate immunity mediated asthma-like inflammation in mice. Inhalation of rCNT elicited a drastic infiltration of eosinophils into the lungs but only minor infiltration of neutrophils and lymphocytes. Transcriptomic study revealed remarkable effec...
ORGANISM(S): Mus musculus 
2014-10-01 | E-GEOD-50176 | biostudies-arrayexpress
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