Mitotic centrosome maturation requires Polo/PLK1-dependent expansion of the pericentriolar material (PCM). In Drosophila, Centrosomin (Cnn) assembles a scaffold around mitotic centrioles through interactions between its PReM and CM2 domains. Here, we show that PReM adopts an autoinhibited helical ha...
Injection of effectors via a type III secretion system (T3SS) is an infection strategy shared by many Gram-negative bacterial pathogens. While individual T3SS effectors are well characterized, their network-level organization and the distinction between core and accessory effectors remain incomplete...
