Sort   by:  
 Page size 
UnknownPhase II Study of Hemithoracic Intensity-Modulated Pleural Radiation Therapy (IMPRINT) As Part of Lung-Sparing Multimodality Therapy in Patients With Malignant Pleural Mesothelioma.
Not available
S-EPMC5019761 | biostudies-literature
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
GenomicsThe Familial Intracranial Aneurysm Linkage Study (FIA)

Our long-term objective is to identify susceptibility genes that are related to the formation of intracranial aneurysms (IA). Rupture of IAs occurs in 16,000 to 17,000 persons in the U.S. annually and nearly half of affected persons are dead within the first 30 days. An additional 6,000 to 7,000 ...

phs000293.v1.p1 | EGA
GenomicsThe National Institute of Neurological Disorders and Stroke (NINDS) Human Genetics Resource Center: DNA and Cell Line Repository (the NINDS Repository): Cerebrovascular Disease/Stroke Study

The National Institute of Neurological Disorders and Stroke (NINDS) Human Genetics Resource Center: DNA and Cell Line Repository (the NINDS Repository), banks phenotypic data and biological samples, including from ...

phs000005.v1.p1 | EGA
GenomicsWhole Exome Sequencing for Familial Intracranial Aneurysm (FIA I-II) Study

The goal of this study is to identify the genes underlying the risk of intracranial aneurysm (IA). The FIA Study initially recruited families appropriate for linkage analysis. Therefore, the recruitment focus was not only on probands with a family history of IA but also required that biological s...

phs000636.v1.p1 | EGA
TranscriptomicsGene expression profiling after induction of WTX in HEK293 cells
WTX encodes a tumor suppressor, frequently inactivated in Wilms tumor, with both plasma membrane and nuclear localization. WTX has been implicated in beta-catenin turnover, but its effect on nuclear proteins is unknown. We report an interaction between WTX and p53, derived from the unexpected observ...
ORGANISM(S): Homo sapiens 
2012-01-01 | E-GEOD-34715 | biostudies-arrayexpress
TranscriptomicsSenescent and myofibroblastic cancer-associated fibroblasts share a contractile phenotype regulated by NOX4 generation of reactive oxygen species in the tumour microenvironment
Cancer associated fibroblasts characterized by an myofibroblastic phenotype play a major role in the tumour microenvironment, being associated with poor prognosis. We found that this cell population is made in part by senescent fibroblasts in vivo. As senescent fibroblasts and myofibroblasts have be...
ORGANISM(S): Homo sapiens 
2017-06-01 | E-MTAB-3101 | biostudies-arrayexpress
TranscriptomicsWTX interacts with the transcriptional regulator TRIM28 to mediate cellular differentiation
WTX encodes a tumor suppressor implicated in Wilms tumor and in mesenchymal differentiation, with distinct functions in the cytoplasm, at the plasma membrane and in the nucleus. Here we report that the transcriptional corepressor TRIM28 is the major binding partner for nuclear WTX. The WTX-TRIM28 in...
ORGANISM(S): Mus musculus 
2015-04-16 | E-GEOD-60418 | biostudies-arrayexpress
UnknownSex-specific modulation of amyloid-β on tau phosphorylation underlies faster tangle accumulation in females.
Not available
S-EPMC10994548 | biostudies-literature
ProteomicsIntegrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer
Explore This Study at the NCI Proteomic Data Commons

ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-08-28 | MSV000084246 | MassIVE
Sort   by:  
 Page size