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TranscriptomicsMulti-tissue functional genomic study of systemic sclerosis
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-01-12 | E-GEOD-76809 | biostudies-arrayexpress
TranscriptomicsNilotinib (Tasigna) in the Treatment of Early Diffuse Systemic Sclerosis: An Open-Label, Pilot Clinical Trial
To assess the safety, efficacy, and molecular change associated with treatment of patients with early, diffuse cutaneous systemic sclerosis (dcSSc) with nilotinib (Tasigna™). In this open-label pilot trial 6 adult patients with early dcSSc received nilotinib. Primary endpoints were safety and change...
ORGANISM(S): Homo sapiens 
2015-08-27 | E-GEOD-65405 | biostudies-arrayexpress
TranscriptomicsFibrotic and Immune Pathway Signatures in Systemic Sclerosis Suggest a Progressive, Multi-step Model of Disease Pathogenesis
Pathway expression analysis in systemic sclerosis revealed key mediators driving pathology within each of the intrinsic gene expression subsets. Genome-wide expression profiling in systemic sclerosis (SSc) has identified four 'intrinsic' subsets of disease (fibroproliferative, inflammatory, limited...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-56308 | biostudies-arrayexpress
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