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MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
UnknownChemoselective Methionine Labelling of Recombinant Trastuzumab Shows High In Vitro and In Vivo Tumour Targeting.
Not available
S-EPMC10946977 | biostudies-literature
GenomicsA Genomic History of Aboriginal Australia
The population history of Aboriginal Australians remains largely uncharacterised. We generated high-coverage genomes for 83 Aboriginal Australians (speakers of Pama-Nyungan languages) and 25 Papuans from the New Guinea Highlands. We find that Papuan and Aboriginal Australian ancestors diversified 25...
EGAS00001001766 | EGA
UnknownSomatostatin 5 receptor expression in prolactinomas: Is there a role for Pasireotide in the management of prolactinomas?
Not available
S-EPMC12583388 | biostudies-literature
UnknownStructural analysis of pathogenic mutations in the DYRK1A gene in patients with developmental disorders.
Not available
S-EPMC5409128 | biostudies-literature
UnknownLiberal or restrictive transfusion in high-risk patients after hip surgery.
Not available
S-EPMC3268062 | biostudies-literature
UnknownNeurodevelopmental outcomes following hematopoietic cell transplantation for patients with severe combined immunodeficiency (SCID): A PIDTC study.
Not available
S-EPMC12829746 | biostudies-literature
UnknownGene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma.
Not available
S-EPMC4014836 | biostudies-literature
UnknownSynthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis.
Not available
S-EPMC12431856 | biostudies-literature
Genomicsena-DATASET-UNIBE-07-04-2016-07:41:15:505-596 - samples
Mapped data (bam files) for high-throughput whole genome sequence data for 83 modern Aboriginal Australians
EGAD00001002001 | EGA
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