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ProteomicsMutant ribosomal protein RPS15 drives B cell malignancy through oxidative stress and genomic instability
Ribosomal protein mutations are increasingly associated with cancer risk and thought to perturb ribosome function. At the same time, they reportedly activate p53, a critical anti-cancer barrier. To determine how these mutations overcome this protective block to enable tumorigenesis, we generated an ...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-01 | PXD071901 | Pride
Mouse Ribosomal protein mutations Chronic lymphocytic leukemia 
UnknownExploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib.
Not available
S-EPMC12001108 | biostudies-literature
UnknownLoss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint Blockade Therapy in Metastatic Uterine Leiomyosarcoma.
Not available
S-EPMC5408320 | biostudies-literature
UnknownClinical Importance of the lncRNA NEAT1 in Cancer Patients Treated with Immune Checkpoint Inhibitors.
Not available
S-EPMC10330151 | biostudies-literature
GenomicsWhole Exome Sequencing of Chronic Lymphocytic Leukemia

The somatic genetic basis of chronic lymphocytic leukemia (CLL), a common and clinically heterogenous adult leukemia, remains poorly understood. Massively parallel sequencing technology now provides a method for systematic discovery of genetic alterations that underlie disease, and for uncovering...

phs000435.v1.p1 | EGA
ProteomicsHLA Class I Presentation of Peptides Derived from ALK Protein
Raw Instrument Data Files in SWATH format. The raw data is submitted as a component of a manuscript: "ALK vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer." Specific format of the SWATH acquisition is described in a supplementary text file.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-23 | MSV000089110 | MassIVE
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