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UnknownWU polyomavirus in children, Canada.
Not available
S-EPMC2876769 | biostudies-literature
ProteomicsAcute proteome responses to de novo sphingolipid synthesis inhibition suggest cancer combination therapies
Sphingolipids are essential structural and signaling lipids that support membrane integrity and govern cell fate decisions. Whereas the consequences of chronic sphingolipid inhibition have been extensively explored, the immediate cellular responses to reduced sphingolipid levels remain poorly define...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD079016 | Pride
Cancer Myriocin Proteome De novo sphingolipid synthesis 
UnknownPolyomaviruses KI and WU in immunocompromised patients with respiratory disease.
Not available
S-EPMC2662633 | biostudies-literature
TranscriptomicsDefault DNA Methylation is Preceded by Broad, Low-Level Transcription in Fetal Male Germ Cells and Is Inversely Patterned by Dynamic H3K4 Methylation (ChIP-chip and MIRA-chip)
To understand what dictates the emerging patterns of de novo DNA methylation, we mapped DNA methylation, chromatin, and transcription changes in purified fetal mouse germ cells using MIRA-chip, ChIP-chip, and strand-specific RNA-seq, respectively. De novo methylation occurred without any apparent tr...
ORGANISM(S): Mus musculus 
2013-07-31 | E-GEOD-45836 | biostudies-arrayexpress
TranscriptomicsDefault DNA Methylation is Preceded by Broad, Low-Level Transcription in Fetal Male Germ Cells and Is Inversely Patterned by Dynamic H3K4 Methylation (RNA-Seq)
To understand what dictates the emerging patterns of de novo DNA methylation, we mapped DNA methylation, chromatin, and transcription changes in purified fetal mouse germ cells using MIRA-chip, ChIP-chip, and strand-specific RNA-seq, respectively. De novo methylation occurred without any apparent tr...
ORGANISM(S): Mus musculus 
2013-07-31 | E-GEOD-46953 | biostudies-arrayexpress
GenomicsA Primary Role of TET Proteins in Establishment and Maintenance of De Novo Bivalency at CpG Islands of Developmental Genes
TET protein-catalyzed 5mC oxidation not only creates novel DNA modifications such as 5hmC, but also initiates active or passive DNA demethylation. However, the TETs’ function in crosstalk with specific histone modifications is largely elusive. Here, we show that TET2-mediated DNA demethylation pla...
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-72481 | biostudies-arrayexpress
UnknownWhole-genome characterization and genotyping of global WU polyomavirus strains.
Not available
S-EPMC2876659 | biostudies-literature
ProteomicsDecoding protein glycosylation by an integrative mass spectrometry-based de novo sequencing strategy
Glycoprotein is one of the most complex biomacromolecule，accounting for over 50% of total human proteins and the majority of biopharmaceuticals, exerting profound influences on various essential biological processes. With multiple N-glycosylation sites and O- glycosylation sites on the protein backb...
ORGANISM(S): Homo Sapiens Bos Taurus 
2024-08-24 | PXD055221 |
UnknownNewly described human polyomaviruses Merkel cell, KI and WU are present in urban sewage and may represent potential environmental contaminants.
Not available
S-EPMC2907336 | biostudies-literature
ProteomicsSoil metaproteomics data analysis based on de novo sequencing with the deep learning-based Kaiko model
We generated a protein database directly from soil metaproteomic data by identifying the microbial composition using the Kaiko model's de novo sequencing methods. We first analyzed the mass spectra de novo (without a database), identifying species from the observed peptides. We next gathered full p...
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
2020-10-20 | MSV000086336 | MassIVE
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