Sort   by:  
 Page size 
TranscriptomicsHigh resolution temporal profiling of gene expression during Arabidopsis leaf development (senescence process)
Leaf senescence is an essential developmental process that involves altered regulation of thousands of genes and changes in many metabolic and signaling pathways resulting in massive physiological and structural changes in the leaf. The regulation of senescence is complex and although several senesc...
ORGANISM(S): Arabidopsis thaliana 
2011-03-24 | E-GEOD-22982 | biostudies-arrayexpress
ProteomicsMetabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | MassIVE
TranscriptomicsA Local Regulatory Network Around Three NAC Transcription Factors in Stress Responses and Senescence in Arabidopsis leaves (expression between lines at timepoints).
A network model has been generated that describes the immediate gene expression cascade surrounding three similar but distinct NAC transcription factors that have roles to play in leaf senescence and in many stress responses in Arabidopsis. ANAC019, ANAC055 and ANAC072 belong to the same clade of N...
ORGANISM(S): Arabidopsis thaliana 
2013-04-23 | E-GEOD-45183 | biostudies-arrayexpress
TranscriptomicsArabidopsis defense against Botrytis cinerea: chronology and regulation deciphered by high-resolution temporal transcriptomic analysis (time series)
A novel experimental design strategy (A Mead et al, in preparation), based on the principle of the M-bM-^@M-^\loop designM-bM-^@M-^], was developed to enable efficient extraction of information about key sample comparisons using a two-colour hybridisation experimental system. With 192 distinct sampl...
ORGANISM(S): Arabidopsis thaliana 
2012-10-02 | E-GEOD-29642 | biostudies-arrayexpress
TranscriptomicsTemporal analysis of physiological, metabolite and transcriptome responses during drought identifies distinct early and late phases in Arabidopsis
Water availability is the biggest single limitation on plant productivity worldwide. In Arabidopsis, adjustments to drought stress, involving changes in metabolism and gene expression drive increased drought tolerance and initiate diverse drought avoidance and escape responses. To address regulatory...
ORGANISM(S): Arabidopsis thaliana 
2016-02-29 | E-GEOD-65046 | biostudies-arrayexpress
UnknownIncidence, Clinical Correlates, and Prognostic Impact of Dementia in Heart Failure: A Population-Based Cohort Study.
Not available
S-EPMC9982209 | biostudies-literature
GenomicsAge related Macular Degeneration (AMD)-- Michigan, Mayo, AREDS, Pennsylvania (MMAP) Cohort Study: A Joint Genome Wide Association Study

Age-related Macular Degeneration (AMD) is a leading cause of incurable blindness in people over the age of 65. AMD is a late-onset multi-factorial neurodegenerative disease and its pathogenesis involves interaction of genetic and environmental factors. Several chromosomal regions have been as...

phs000182.v2.p1 | EGA
MetabolomicsGNPS - Targeting FSP1 triggers ferroptosis in lung cancer
Raw mass spectrometry data were acquired via LC-MS to quantify oxidized lipids and Coenzyme Q9 (CoQ9) in mouse lung tumor and cell line samples. A Parallel Reaction Monitoring (PRM) strategy was employed for oxidized lipids, while a Data-Dependent Acquisition (DDA) method was used for CoQ9.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-08-19 | MSV000098883 | GNPS
TranscriptomicsRNA-Seq of Single Prostate CTCs Implicates Non-Canonical Wnt Signaling in Antiandrogen Resistance
Prostate cancer is initially responsive to androgen deprivation, but the effectiveness of androgen receptor (AR) inhibitors in recurrent disease is variable. Biopsy of bone metastases is challenging, hence sampling circulating tumor cells (CTCs) may reveal drug resistance mechanisms. We established ...
ORGANISM(S): Homo sapiens 
2015-09-17 | E-GEOD-67980 | biostudies-arrayexpress
MetabolomicsGNPS - Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
The genomic landscape of colorectal cancer (CRC) is shaped by inactivating mutations in tumour suppressors such as APC, and oncogenic mutations such as mutant KRAS. Here we used genetically engineered mouse models (GEMMs), and multimodal mass spectrometry-based metabolomics to study the impact of co...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-07-18 | MSV000092468 | GNPS
Sort   by:  
 Page size