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GenomicsGenome-wide maps of H3K27me3 in WT (wild type) and Epi-df (mutant) rice
DNA methylation and histone H3 lysine 9 dimethylation (H3K9me2) are important epigenetic repression marks for silencing transposons in heterochromatin and regulating gene expression in plant development. However, the mechanistic relationship to other repressive marks, such as histone H3 lysine 27 tr...
ORGANISM(S): Oryza sativa 
2013-12-04 | E-GEOD-40674 | biostudies-arrayexpress
TranscriptomicsComparison of transcriptome profile between wild-type and Epi-df mutant plants
We identified and characterized a rice epigenetic mutant Epi-df which exhibits a dwarf stature and various floral defects that are inherited in a dominant fashion. We demonstrated that Epi-df participates in Polycomb repressive complex 2 (PRC2) mediated gene silencing. Epigenetic mutations results i...
ORGANISM(S): Oryza sativa Japonica Group 
2012-07-12 | E-GEOD-39298 | biostudies-arrayexpress
GenomicsMapping ONECUT1 TF binding with ChIP-exo
The aim of this project is to locate the precise binding of the ONECUT1 transcription factor. NOTE: This study was updated on 7th May 2014. All samples, experiments, runs and files were replaced. This was due to an incorrect reagent being used in the earlier version.
ORGANISM(S): Mus musculus 
2014-05-10 | E-MTAB-2060 | biostudies-arrayexpress
TranscriptomicsThe G-protein Alpha Subunit Gsα Is A Tumor Suppressor In Sonic Hedgehog-driven Medulloblastoma [Microarray expression]
Medulloblastoma, the most common malignant pediatric brain tumor, is highly heterogeneous with distinct molecular subtypes and cellular origins. Although current treatments improve survival rates, patients suffer severe treatment-related side effects and often relapse of tumors carrying resistance m...
ORGANISM(S): Mus musculus 
2014-08-24 | E-GEOD-60417 | biostudies-arrayexpress
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