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TranscriptomicsC9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD
Noncoding expansions of a hexanucleotide repeat (GGGGCC) in the C9orf72 gene are the most common cause of familial amyotrophic lateral sclerosis and frontotemporal dementia. Here we report transgenic mice carrying a bacterial artificial chromosome (BAC) containing the full human C9orf72 gene with ei...
ORGANISM(S): Mus musculus 
2016-02-10 | E-GEOD-77720 | biostudies-arrayexpress
UnknownMitosis-specific acetylation tunes Ran effector binding for chromosome segregation.
Not available
S-EPMC6041754 | biostudies-literature
ProteomicsCD47 interactions with exportin-1 regulate targeting of m7G-capped RNAs to extracellular vesicles
CD47 is a marker of self and a signaling receptor for thrombospondin-1 that is also a membrane component of extracellular vesicles (EVs) released by various cell types. Previous studies identified CD47-dependent functional effects of EVs on target cells, mediated by delivery of their RNA contents, a...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-01 | MSV000086969 | MassIVE
UnknownGraphene tailored by Fe3O4 nanoparticles: low-adhesive and durable superhydrophobic coatings.
Not available
S-EPMC9064432 | biostudies-literature
UnknownGreen Synthesis of Au-NPs on g-C3N4 Hybrid Nanomaterials Based on Supramolecular Pillar[6]arene and Its Applications for Catalysis.
Not available
S-EPMC9161382 | biostudies-literature
TranscriptomicsRNA-seq of 36 individuals with autism spectrum disorder
To assess the clinical impact of splice-altering noncoding mutations in autism spectrum disorder (ASD), we used a deep learning framework (SpliceAI) to predict the splice-altering potential of de novo mutations in 3,953 individuals with ASD from the Simons Simplex Collection. To validate these predi...
ORGANISM(S): Homo sapiens 
2018-11-25 | E-MTAB-7351 | biostudies-arrayexpress
Unknowntrans-Stilbenoids with Extended Fluorescence Lifetimes for the Characterization of Amyloid Fibrils.
Not available
S-EPMC6641930 | biostudies-literature
ProteomicsRheb and TRF1 PhastID mass spectrometric data
Rheb is a small G protein that functions as the direct activator of the mechanistic target of rapamycin complex 1 (mTORC1) to coordinate signaling cascades in response to nutrients and growth factors. Despite extensive studies, the guanine nucleotide exchange factor (GEF) that directly activates Rhe...
ORGANISM(S): Homo Sapiens 
2022-09-29 | PXD037078 |
UnknownDifferential regulation of mTOR activity in retinal ganglion cells underlies their distinct susceptibility to ischemia/reperfusion.
Not available
S-EPMC12159190 | biostudies-literature
UnknownTransthyretin Binding Mode Dichotomy of Fluorescent trans-Stilbene Ligands.
Not available
S-EPMC9982997 | biostudies-literature
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