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Individuals of African descent in the United States suffer disproportionately from diseases with a metabolic etiology (obesity, metabolic syndrome, and diabetes), and from the pathological consequences of these disorders (hypertension and cardiovascular disease). Using a combination of genetic/geno...
ORGANISM(S): Homo sapiens 
Study the impact of the most common mutation on the PML protein found in acute promyeocytic leukemia patients resistant to arsenic therapy, which induces a disorganization of PML nuclear bodies, on gene expression.
ORGANISM(S): Mus musculus 
Study the impact of the most common mutation on the PML protein found in acute promyeocytic leukemia patients resistant to arsenic therapy, which induces a disorganization of PML nuclear bodies, on gene expression.
ORGANISM(S): Mus musculus 
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